Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
0.320 Biomarker disease CLINGEN
Entrez Id: 1111
Gene Symbol: CHEK1
CHEK1
0.320 Biomarker disease CLINGEN
Entrez Id: 8493
Gene Symbol: PPM1D
PPM1D
0.310 GeneticVariation disease ORPHANET
Entrez Id: 5002
Gene Symbol: SLC22A18
SLC22A18
0.300 GeneticVariation disease ORPHANET
Entrez Id: 8438
Gene Symbol: RAD54L
RAD54L
0.300 GeneticVariation disease ORPHANET
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
0.300 Biomarker disease CLINGEN
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.300 Biomarker disease CLINGEN
Entrez Id: 5979
Gene Symbol: RET
RET
0.100 CausalMutation disease CLINVAR
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.400 GeneticVariation disease BEFREE <b>Expert opinion</b>: The transition to multi-gene panels in breast cancer patients has improved the likelihood of capturing a rare variant in a well-established gene associated with hereditary breast cancer (e.g.<i>BRCA1 and BRCA2, TP53</i>). 31469018 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.400 GeneticVariation disease BEFREE <b>Expert opinion</b>: The transition to multi-gene panels in breast cancer patients has improved the likelihood of capturing a rare variant in a well-established gene associated with hereditary breast cancer (e.g.<i>BRCA1 and BRCA2, TP53</i>). 31469018 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.080 Biomarker disease BEFREE 655Val and 1170Pro ERBB2 SNPs in familial breast cancer risk and BRCA1 alterations. 17452776 2007
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.400 GeneticVariation disease BEFREE 655Val and 1170Pro ERBB2 SNPs in familial breast cancer risk and BRCA1 alterations. 17452776 2007
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.400 GeneticVariation disease BEFREE Hereditary breast cancer due to mutations in BRCA1 and BRCA2 was a heterogeneous syndrome in the southeastern United States. 10767783 2000
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.400 GeneticVariation disease BEFREE Hereditary breast cancer due to mutations in BRCA1 and BRCA2 was a heterogeneous syndrome in the southeastern United States. 10767783 2000
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.400 GeneticVariation disease BEFREE Hereditary breast cancer associated with a germline BRCA2 mutation in identical female twins with similar disease expression. 11890985 2002
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.400 GeneticVariation disease BEFREE Hereditary breast cancer is characterized by an inherited susceptibility to breast cancer on basis of an identified germline mutation in one allele of a high penetrance susceptibility gene (such as BRCA1, BRCA2, CHEK 2, TP53 or PTEN). 15351094 2004
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.400 GeneticVariation disease BEFREE Hereditary breast cancer is characterized by an inherited susceptibility to breast cancer on basis of an identified germline mutation in one allele of a high penetrance susceptibility gene (such as BRCA1, BRCA2, CHEK 2, TP53 or PTEN). 15351094 2004
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.060 GeneticVariation disease BEFREE Hereditary breast cancer is characterized by an inherited susceptibility to breast cancer on basis of an identified germline mutation in one allele of a high penetrance susceptibility gene (such as BRCA1, BRCA2, CHEK 2, TP53 or PTEN). 15351094 2004
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.400 Biomarker disease BEFREE Familial breast cancer: characteristics and outcome of BRCA 1-2 positive and negative cases. 15996267 2005
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.400 GeneticVariation disease BEFREE Hereditary breast cancer has been partly attributed to germline mutations in the BRCA1 gene that are deleterious for BRCA1 protein activity. 16026807 2005
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.400 GeneticVariation disease BEFREE Familial breast cancer is associated with mutations in several genes (BRCA1, BRCA2, p53, ATM) whose protein products protect against radiation-induced genotoxicity. 16777992 2006
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.400 GeneticVariation disease BEFREE Familial breast cancer is associated with mutations in several genes (BRCA1, BRCA2, p53, ATM) whose protein products protect against radiation-induced genotoxicity. 16777992 2006
Entrez Id: 472
Gene Symbol: ATM
ATM
0.400 GeneticVariation disease BEFREE Familial breast cancer is associated with mutations in several genes (BRCA1, BRCA2, p53, ATM) whose protein products protect against radiation-induced genotoxicity. 16777992 2006
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.400 GeneticVariation disease BEFREE Familial breast cancer: double heterozygosity for BRCA1 and BRCA2 mutations with differing phenotypes. 17636421 2008
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.400 GeneticVariation disease BEFREE Familial breast cancer: double heterozygosity for BRCA1 and BRCA2 mutations with differing phenotypes. 17636421 2008