Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
0.320 Biomarker disease CLINGEN
Entrez Id: 1111
Gene Symbol: CHEK1
CHEK1
0.320 Biomarker disease CLINGEN
Entrez Id: 8493
Gene Symbol: PPM1D
PPM1D
0.310 GeneticVariation disease ORPHANET
Entrez Id: 5002
Gene Symbol: SLC22A18
SLC22A18
0.300 GeneticVariation disease ORPHANET
Entrez Id: 8438
Gene Symbol: RAD54L
RAD54L
0.300 GeneticVariation disease ORPHANET
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
0.300 Biomarker disease CLINGEN
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.300 Biomarker disease CLINGEN
Entrez Id: 5979
Gene Symbol: RET
RET
0.100 CausalMutation disease CLINVAR
Entrez Id: 5617
Gene Symbol: PRL
PRL
0.020 Biomarker disease BEFREE The levels of BLH were highly correlated with the sum of ir-PRL and ir-GH in both the familial breast cancer group and the controls (P less than 0.001 for both groups by Spearman's rank correlation test). 2632255 1989
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.010 GeneticVariation disease BEFREE Polymorphism of the c-Ha-ras-1 proto-oncogene in sporadic and familial breast cancer. 2668204 1989
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.310 Biomarker disease CLINGEN E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. 2007622 1991
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.100 GeneticVariation disease BEFREE A much smaller proportion of familial breast cancer is accounted for by mutations in the p53 gene (17p13). 1511156 1992
Entrez Id: 5245
Gene Symbol: PHB
PHB
0.030 GeneticVariation disease BEFREE We have isolated the human homologue of the rat prohibitin gene and mapped it to chromosome 17q12-21 where a gene responsible for hereditary breast cancer was localized. 1540973 1992
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.400 GeneticVariation disease BEFREE A somatic cell hybrid map of the long arm of human chromosome 17, containing the familial breast cancer locus (BRCA1). 8460635 1993
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.400 GeneticVariation disease BEFREE Three loci have been implicated in the etiology of familial breast cancer; the BRCA1 locus on 17q, the p53 gene on 17p, and the androgen receptor gene on the X chromosome. 8364930 1993
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.400 GeneticVariation disease BEFREE A gene designated BRCA1, implicated in the susceptibility to early-onset familial breast cancer, has recently been localized to chromosome 17q12-q21. 8244379 1993
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.100 GeneticVariation disease BEFREE No mutation was found in any patient, confirming that germline mutations of the P53 gene are very rare in familial breast cancer (apart from Li Fraumeni families). 8398277 1993
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.400 GeneticVariation disease BEFREE The hereditary breast cancer gene BRCA1 previously has been localized to chromosome 17q21. 8168077 1994
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.400 Biomarker disease BEFREE Familial breast cancer. BRCA1 down, BRCA2 to go. 7874485 1994
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.400 Biomarker disease BEFREE The gene encoding this enzyme, EDH17B2, has been mapped to chromosome 17, region q12-q21, in the vicinity of BRCA1, as as yet unidentified gene that appears to be involved in familial breast cancer and in familial ovarian cancer. 8125484 1994
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.400 Biomarker disease BEFREE These results suggest that BRCA1 is not a major breast cancer susceptibility gene in Japanese familial breast cancer. 7852187 1994
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.400 Biomarker disease BEFREE There are, however, at least three loci known to be associated with familial breast cancer (p53, BRCA1, and an as yet unpublished locus) and the frequencies and penetrances of these genes are not likely to be the same. 7891376 1994
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.310 Biomarker disease CLINGEN Point mutation of the E-cadherin gene in invasive lobular carcinoma of the breast. 7961105 1994
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.100 GeneticVariation disease BEFREE Frequent p53 gene mutations and novel alleles in familial breast cancer. 8033087 1994
Entrez Id: 3294
Gene Symbol: HSD17B2
HSD17B2
0.030 Biomarker disease BEFREE The gene encoding this enzyme, EDH17B2, has been mapped to chromosome 17, region q12-q21, in the vicinity of BRCA1, as as yet unidentified gene that appears to be involved in familial breast cancer and in familial ovarian cancer. 8125484 1994