Gene: XRCC2 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7516
Gene Symbol: XRCC2
XRCC2 		0.530 GeneticVariation disease BEFREE We identified a recurrent truncating mutation of XRCC2 (c.96delT, p.Phe32fs) in 3 of 617 patients with familial breast cancer who were sequenced. 31463769 2019
Entrez Id: 7516
Gene Symbol: XRCC2
XRCC2 		0.530 GeneticVariation disease BEFREE Variants in XRCC2 are unlikely to explain a substantial proportion of familial breast cancer. 23054243 2012
Entrez Id: 7516
Gene Symbol: XRCC2
XRCC2 		0.530 Biomarker disease CLINGEN Rare mutations in XRCC2 increase the risk of breast cancer. 22464251 2012
Entrez Id: 7516
Gene Symbol: XRCC2
XRCC2 		0.530 SusceptibilityMutation disease ORPHANET Rare mutations in XRCC2 increase the risk of breast cancer. 22464251 2012
Entrez Id: 7516
Gene Symbol: XRCC2
XRCC2 		0.530 GeneticVariation disease BEFREE These data establish seven SNPs - hPRB +331G/A, AR CAG repeat, CYP19 (TTTA)10, CYP1A1 MspI, VDR FOK1, XRCC1 Arg194Trp and XRCC2 Arg188His - as small but significant risk factors for spontaneous, non-hereditary breast cancer. 16835078 2006
Entrez Id: 7516
Gene Symbol: XRCC2
XRCC2 		0.530 Biomarker disease CLINGEN Homologous recombination deficiency leads to profound genetic instability in cells derived from Xrcc2-knockout mice. 14678973 2003
Entrez Id: 7516
Gene Symbol: XRCC2
XRCC2 		0.530 Biomarker disease CLINGEN Xrcc2 is required for genetic stability, embryonic neurogenesis and viability in mice. 11118202 2000
Entrez Id: 7516
Gene Symbol: XRCC2
XRCC2 		0.530 Biomarker disease CLINGEN The XRCC2 and XRCC3 repair genes are required for chromosome stability in mammalian cells. 10422536 1999