×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.310
GeneticVariation
disease
BEFREE
Using Exome Aggregation Consortium control data, we confirm significant associations of heterozygous germ line mutations with BC for ATM (OR: 3.63, 95%CI: 2.67-4.94), CDH1 (OR: 17.04, 95%CI: 3.54-82), CHEK2 (OR: 2.93, 95%CI: 2.29-3.75), PALB2 (OR: 9.53, 95%CI: 6.25-14.51), and TP53 (OR: 7.30, 95%CI: 1.22-43.68).
29522266
2018
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.310
Biomarker
disease
CLINGEN
Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond.
26182300
2015
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.310
Biomarker
disease
CLINGEN
Germline CDH1 mutations in bilateral lobular carcinoma in situ.
24366306
2014
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.310
Biomarker
disease
CLINGEN
Clinical evaluation of a multiple-gene sequencing panel for hereditary cancer risk assessment.
24733792
2014
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.310
Biomarker
disease
CLINGEN
CDH1 germline mutations and the hereditary diffuse gastric and lobular breast cancer syndrome: a multicentre study.
23709761
2013
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.310
Biomarker
disease
CLINGEN
The importance of E-cadherin binding partners to evaluate the pathogenicity of E-cadherin missense mutations associated to HDGC.
22850631
2013
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.310
Biomarker
disease
CLINGEN
E-cadherin promotor methylation and mutation are inversely related to motility capacity of breast cancer cells.
23053649
2012
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.310
Biomarker
disease
CLINGEN
Germline mutations of the E-cadherin gene in families with inherited invasive lobular breast carcinoma but no diffuse gastric cancer.
21271559
2011
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.310
Biomarker
disease
CLINGEN
Germline E-cadherin mutations in familial lobular breast cancer.
17660459
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.310
Biomarker
disease
CLINGEN
Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.
17097565
2006
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.310
Biomarker
disease
CLINGEN
Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14.
10074450
1999
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.310
Biomarker
disease
CLINGEN
Point mutation of the E-cadherin gene in invasive lobular carcinoma of the breast.
7961105
1994
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.310
Biomarker
disease
CLINGEN
E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells.
2007622
1991