Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2776
Gene Symbol: GNAQ
GNAQ 		0.400 Biomarker disease HPO
Entrez Id: 8314
Gene Symbol: BAP1
BAP1 		0.400 Biomarker disease HPO
Entrez Id: 2767
Gene Symbol: GNA11
GNA11 		0.400 Biomarker disease HPO
Entrez Id: 57105
Gene Symbol: CYSLTR2
CYSLTR2 		0.400 Biomarker disease HPO
Entrez Id: 23451
Gene Symbol: SF3B1
SF3B1 		0.400 Biomarker disease HPO
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		0.010 AlteredExpression disease BEFREE Choroidal melanoma is the most common intraocular tumor in adults, and overexpression of matrix metalloproteinase-2 or matrix metalloproteinase-9 (MMP-2/MMP-9) is associated with angiogenesis and tumor metastasis of the choroidal malignant melanoma (CMM). 29260433 2018
Entrez Id: 654231
Gene Symbol: OCM
OCM 		0.010 Biomarker disease BEFREE OCM1 and B16F10 animal models of choroidal melanoma were established. 29625446 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.010 AlteredExpression disease BEFREE VEGF protein was expressed in CM in all 20 cases of CM, especially along the VM. 31380420 2019
Entrez Id: 5599
Gene Symbol: MAPK8
MAPK8 		0.010 AlteredExpression disease BEFREE Cepharanthine exerts antitumor activity on choroidal melanoma by reactive oxygen species production and c-Jun N-terminal kinase activation. 28529590 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.020 AlteredExpression disease BEFREE Chromosomal abnormalities, p53 and Bcl-2 expression and clinical outcome in choroidal melanoma. 15577317 2004
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.010 AlteredExpression disease BEFREE Chromosomal abnormalities, p53 and Bcl-2 expression and clinical outcome in choroidal melanoma. 15577317 2004
Entrez Id: 2247
Gene Symbol: FGF2
FGF2 		0.010 AlteredExpression disease BEFREE Correlation between ERG changes and FGF2 mRNA Up-regulation in patients with choroidal melanoma. 12137767 2002
Entrez Id: 64065
Gene Symbol: PERP
PERP 		0.010 AlteredExpression disease BEFREE Differential expression of PERP was identified in primary choroidal melanoma specimens, both at transcriptional and protein level. 16784742 2006
Entrez Id: 8314
Gene Symbol: BAP1
BAP1 		0.400 SomaticCausalMutation disease ORPHANET Frequent mutation of BAP1 in metastasizing uveal melanomas. 21051595 2010
Entrez Id: 4921
Gene Symbol: DDR2
DDR2 		0.100 GeneticVariation disease GWASCAT Genome-wide study on uveal melanoma patients finds association to DNA repair gene TDP1. 31626034 2020
Entrez Id: 753
Gene Symbol: LDLRAD4
LDLRAD4 		0.100 GeneticVariation disease GWASCAT Genome-wide study on uveal melanoma patients finds association to DNA repair gene TDP1. 31626034 2020
Entrez Id: 2767
Gene Symbol: GNA11
GNA11 		0.400 SomaticCausalMutation disease ORPHANET Genomic, prognostic, and cell-signaling advances in uveal melanoma. 23714557 2013
Entrez Id: 2776
Gene Symbol: GNAQ
GNAQ 		0.400 SomaticCausalMutation disease ORPHANET Genomic, prognostic, and cell-signaling advances in uveal melanoma. 23714557 2013
Entrez Id: 23451
Gene Symbol: SF3B1
SF3B1 		0.400 Biomarker disease ORPHANET Genomic, prognostic, and cell-signaling advances in uveal melanoma. 23714557 2013
Entrez Id: 8314
Gene Symbol: BAP1
BAP1 		0.400 GermlineCausalMutation disease ORPHANET Germline BAP1 mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancers. 21941004 2011
Entrez Id: 4082
Gene Symbol: MARCKS
MARCKS 		0.010 AlteredExpression disease BEFREE Here we compare the expression of MARCKS in human tumor-derived choroidal melanoma cells (OCM-1) and in primary cultures of normal choroidal melanocytes. 9537244 1998
Entrez Id: 883
Gene Symbol: KYAT1
KYAT1 		0.010 Biomarker disease BEFREE Immunohistochemistry was conducted using polyclonal antibodies against KAT I, II, and III on sections of eight enucleated eyes from patients with choroidal melanoma. 28706436 2017
Entrez Id: 8520
Gene Symbol: HAT1
HAT1 		0.010 Biomarker disease BEFREE Immunohistochemistry was conducted using polyclonal antibodies against KAT I, II, and III on sections of eight enucleated eyes from patients with choroidal melanoma. 28706436 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.020 GeneticVariation disease BEFREE Increased expression and mutation of p53 in choroidal melanoma. 1419633 1992
Entrez Id: 2776
Gene Symbol: GNAQ
GNAQ 		0.400 SomaticCausalMutation disease ORPHANET Mutations in GNA11 in uveal melanoma. 21083380 2010