×
Entrez Id:
5932
Gene Symbol:
RBBP8
RBBP8
0.300
CausalMutation
disease
CGI
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
0.600
AlteredExpression
disease
BEFREE
Activation of c-Ki-ras gene in human pancreatic cancer .
3932275
1985
×
Entrez Id:
3265
Gene Symbol:
HRAS
HRAS
0.100
AlteredExpression
disease
BEFREE
Activation of c-Ki-ras gene in human pancreatic cancer .
3932275
1985
SERPINA1
0.030
Biomarker
disease
BEFREE
The mean value of alpha 1-AT (+/- SEM) in cases with cancer of the pancreas was 486 (+/- 18) mg/100 ml, and it was significantly higher than the corresponding mean value in controls, which was 434 (+/- 13) mg/100 ml (p approximately 0.02).
3872237
1985
×
Entrez Id:
1956
Gene Symbol:
EGFR
EGFR
0.400
AlteredExpression
disease
BEFREE
Enhanced expression of epidermal growth factor receptor correlates with alterations of chromosome 7 in human pancreatic cancer .
3014534
1986
×
Entrez Id:
6750
Gene Symbol:
SST
SST
0.400
Therapeutic
disease
CTD_human
[Vipoma. 9-year observations using currently available therapy methods].
2868874
1986
×
Entrez Id:
1950
Gene Symbol:
EGF
EGF
0.100
AlteredExpression
disease
BEFREE
Our results suggest that enhanced expression of EGF receptor in human pancreatic cancer can be associated with either structural or numerical alterations of chromosome 7.
3014534
1986
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
0.600
GeneticVariation
disease
BEFREE
Frequency and types of point mutation at the 12th codon of the c-Ki-ras gene found in pancreatic cancers from Japanese patients.
2507485
1989
×
Entrez Id:
3265
Gene Symbol:
HRAS
HRAS
0.100
GeneticVariation
disease
BEFREE
Frequency and types of point mutation at the 12th codon of the c-Ki-ras gene found in pancreatic cancers from Japanese patients.
2507485
1989
×
Entrez Id:
3265
Gene Symbol:
HRAS
HRAS
0.100
GeneticVariation
disease
BEFREE
Loss of the same alleles of HRAS1 and D11S151 in two independent pancreatic cancers from a patient with multiple endocrine neoplasia type 1.
2565762
1989
×
Entrez Id:
4893
Gene Symbol:
NRAS
NRAS
0.040
GeneticVariation
disease
BEFREE
Loss of the same alleles of HRAS1 and D11S151 in two independent pancreatic cancers from a patient with multiple endocrine neoplasia type 1.
2565762
1989
×
Entrez Id:
8045
Gene Symbol:
RASSF7
RASSF7
0.010
GeneticVariation
disease
BEFREE
Loss of the same alleles of HRAS1 and D11S151 in two independent pancreatic cancers from a patient with multiple endocrine neoplasia type 1.
2565762
1989
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
0.600
GeneticVariation
disease
BEFREE
Frequent glycine-to-aspartic acid mutations at codon 12 of c-Ki-ras gene in human pancreatic cancer in Japanese.
2110130
1990
×
Entrez Id:
3265
Gene Symbol:
HRAS
HRAS
0.100
GeneticVariation
disease
BEFREE
Frequent glycine-to-aspartic acid mutations at codon 12 of c-Ki-ras gene in human pancreatic cancer in Japanese.
2110130
1990
×
Entrez Id:
885
Gene Symbol:
CCK
CCK
0.100
Biomarker
disease
BEFREE
The effect of a synthetic analogue of CCK (Thr4,Nle7CCK-9) on growth of SW-1990 human pancreatic cancer was examined in two experimental models.
2226098
1990
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.800
Biomarker
disease
BEFREE
One of the antibodies, CM1, recognises p53 in formalin-fixed, paraffin-embedded archival material and using this reagent we found immunodetectable p53 in 28 of 124 (23%) pancreatic cancers .
1764370
1991
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
0.600
GeneticVariation
disease
BEFREE
With regard to pancreatic cancers , the authors' data confirm the very high frequency (88.6%) of Ki-ras gene mutations occurring at codon 12.
1741644
1991
×
Entrez Id:
3265
Gene Symbol:
HRAS
HRAS
0.100
GeneticVariation
disease
BEFREE
With regard to pancreatic cancers , the authors' data confirm the very high frequency (88.6%) of Ki-ras gene mutations occurring at codon 12.
1741644
1991
×
Entrez Id:
8190
Gene Symbol:
MIA
MIA
0.100
Biomarker
disease
BEFREE
Well- to moderately-differentiated SW1990 and CAPAN-2 human pancreatic cancer cells were found to produce more high-Mr glycoprotein (HMG) than less-differentiated MIA PaCa-2 and PANC-1 cells.
2064602
1991
×
Entrez Id:
3008
Gene Symbol:
H1-4
H1-4
0.010
Biomarker
disease
BEFREE
These results indicate that the AC inhibitor in the pancreatic cancer extract is histone H1b or H1d and histones H2A, H2B and H3 also have an AC inhibitory activity.
2018521
1991
×
Entrez Id:
3009
Gene Symbol:
H1-5
H1-5
0.010
Biomarker
disease
BEFREE
These results indicate that the AC inhibitor in the pancreatic cancer extract is histone H1b or H1d and histones H2A, H2B and H3 also have an AC inhibitory activity.
2018521
1991
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.800
GeneticVariation
disease
BEFREE
Alterations in the p53 and Rb-1 genes may be important features in the development of human pancreatic cancer .
1630814
1992
×
Entrez Id:
1956
Gene Symbol:
EGFR
EGFR
0.400
AlteredExpression
disease
BEFREE
Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha.
1401070
1992
×
Entrez Id:
324
Gene Symbol:
APC
APC
0.400
GeneticVariation
disease
BEFREE
Frequent somatic mutations of the APC gene in human pancreatic cancer .
1423316
1992
×
Entrez Id:
5925
Gene Symbol:
RB1
RB1
0.330
Biomarker
disease
BEFREE
Alterations in the p53 and Rb-1 genes may be important features in the development of human pancreatic cancer .
1630814
1992