| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | GeneticVariation | disease | BEFREE | In functional experiments, we found subjects carrying the minor alleles of rs4759314 and rs200349340 had significantly higher HOTAIR RNA levels (mean ± SD) than those carrying the major alleles in PC tissues. | 30867650 | 2019 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | The aim of our study was to investigate the contribution of two lncRNAs polymorphisms (rs1561927 and rs4759313 of PVT1 and HOTAIR, respectively) in PC susceptibility. | 30475759 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | Inhibition of long non-coding RNA HOTAIR enhances radiosensitivity via regulating autophagy in pancreatic cancer. | 30464623 | 2018 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Epigenetic regulation plays important roles in tumor pathogenesis and resistance, and a recent study indicated that the long non-coding RNA HOX transcript antisense RNA (HOTAIR) is overexpressed in pancreatic cancer. | 28476883 | 2017 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | LncRNA HOTAIR acts a competing endogenous RNA to control the expression of notch3 via sponging miR-613 in pancreatic cancer. | 28415631 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | WITHDRAWN: Epigenetic silence of HOTAIR contributes to the metastasis of pancreatic cancer via targeting miR-138. | 29268816 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | In summary, our studies demonstrated that miR-663b is epigenetically repressed by HOTAIR and exerts its tumor-suppressive function via targeting IGF2 in pancreatic cancer. | 27895308 | 2016 | ||||
|
0.090 | Biomarker | disease | BEFREE | The long non-coding RNA Hox transcript antisense intergenic RNA (HOTAIR) was recently implicated in breast cancer metastasis and is predictive of poor prognosis in colorectal and pancreatic cancers. | 25428914 | 2015 | ||||
|
0.090 | Biomarker | disease | BEFREE | HOTAIR knockdown in L3.6pL cells inhibited tumor growth in mouse xenograft model, further demonstrating the pro-oncogenic function of HOTAIR in pancreatic cancer. | 22614017 | 2013 |