Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.360 | AlteredExpression | disease | BEFREE | The expression of hENT1 and DPD were analyzed in patients registered in the JASPAC 01 trial which showed a better survival of S-1 over GEM as adjuvant chemotherapy after resection for pancreatic cancer, and their possible roles for predicting treatment outcomes and selecting a chemotherapeutic agent were investigated. | 31778273 | 2020 | ||||
|
0.360 | Biomarker | disease | BEFREE | DPD and hENT1 immunohistochemistry and scoring was completed on tumour cores from 238 patients with pancreatic cancer in the ESPAC-3(v2) trial, randomised to either postoperative gemcitabine or 5-fluorouracil/folinic acid (5FU/FA). | 29515256 | 2018 | ||||
|
0.360 | AlteredExpression | disease | BEFREE | Clinical implications of dihydropyrimidine dehydrogenase expression in patients with pancreatic cancer who undergo curative resection with S-1 adjuvant chemotherapy. | 28789372 | 2017 | ||||
|
0.360 | AlteredExpression | disease | BEFREE | We found that DPD mRNA was higher in patients with pancreatic cancers than those with gastric cancers, colon cancers, and liver cancers. | 21210725 | 2011 | ||||
|
0.360 | AlteredExpression | disease | BEFREE | Accordingly, intratumoral DPD mRNA expression level was measured to reveal whether the level in pancreatic cancer was different from other GI cancer and whether it was relevant to chemosensitivity. | 18309485 | 2008 | ||||
|
0.360 | Biomarker | disease | BEFREE | The objectives of this phase II study were to evaluate the effect of radiation (XRT) on thymidine phosphorylase (TP), dihydropyrimidine dehydrogenase (DPD), and tumor necrosis factor-alpha (TNF-alpha) and the efficacy of capecitabine-XRT in patients with locally advanced pancreatic cancer. | 17762760 | 2007 |