Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | Biomarker | disease | BEFREE | miR-29a is repressed by MYC in pancreatic cancer and its restoration drives tumor suppressive effects via downregulation of LOXL2. | 31662451 | 2020 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | We first found that DRP1 was substantially upregulated in PC cell lines and tissue samples mainly due to the downregulation of miR-29a, which contributed to the poor survival of PC patients. | 31674061 | 2019 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | MiR-29a, targeting caveolin 2 expression, is responsible for limitation of pancreatic cancer metastasis in patients with normal level of serum CA125. | 29978477 | 2018 | ||||
|
0.070 | Biomarker | disease | BEFREE | If these results are extended to other models of pancreatic cancer, they would reduce the attractiveness of miR-29a as a potential therapeutic target in pancreatic cancer. | 28460473 | 2017 | ||||
|
0.070 | Biomarker | disease | BEFREE | Our results suggest that miR-29a acts as an oncogene by down regulating TTP and provide the basis for further studies exploring the potential of miR-29a and TTP as biomarkers and targets for the treatment of pancreatic cancer. | 26356262 | 2015 | ||||
|
0.070 | Biomarker | disease | BEFREE | Pathophysiological role of microRNA-29 in pancreatic cancer stroma. | 26095125 | 2015 | ||||
|
0.070 | Biomarker | disease | BEFREE | Collectively, our findings identified CEACAM6, which is regulated by miR-29a/b/c, as an important positive regulator of EMT in pancreatic cancer offering an explanation for how elevated levels of CEACAM6 are likely to contribute to the highly metastatic phenotype of pancreatic cancer. | 23857344 | 2013 |