The present study evaluated the role of CD147 in the tumorigenesis of SCC of the tongue <i>in vitro</i>, as well as the association between CD147 expression and cervical lymph node metastasis in clinical samples of SCC of the tongue.
Levels of MACC1 and EMMPRIN expression were analyzed in 65 paraffin‑embedded tissue specimens of TSCC and in the adjacent non-cancerous tissues using immunohistochemistry (IHC).