| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.060 | AlteredExpression | disease | BEFREE | The AUC with the LA-FINDRISC vs. the O-FINDRISC were: for uT2D, 0.722 vs. 0.729 in men (p=0.854) and 0.724 vs. 0.732 in women (p=0.896); for prediabetes (impaired fasting glucose [IFG] + impaired glucose tolerance [IGT], 0.590 vs. 0.587 in men (p=0.887) and 0.621 vs. 0.627 in women (p=0.777); for IFG, 0.582 vs. 0.580 in men (p=0.924) and 0.607 vs. 0.617 in women (p=0.690); for IGT, 0.691 vs. 0.692 in men (p=0.971) and 0.672 vs. 0.671 in women (p=0.974). | 31202539 | 2019 | ||||
|
0.060 | GeneticVariation | disease | BEFREE | Among the 152 subjects with prediabetes (IFG and/or IGT), two groups each with 20 individuals, having the lowest and highest pancreatic fat content were selected. | 31096268 | 2019 | ||||
|
0.060 | Biomarker | disease | BEFREE | We then found that circulating CILP-2 levels had a progressive increase from normal to IGT (a pre-diabetic status) and then to diabetes, which was correlated positively with WHR, triglyceride, FBG, 2-h blood glucose after glucose overload (2h-BG), HbA1c, FIns, 2h-Ins, and HOMA-IR but negatively with HDL-C. CILP-2 expression was increased in the liver and muscle but decreased in adipose tissues of obese mice or T2DM patients. | 30896018 | 2019 | ||||
|
0.060 | GeneticVariation | disease | BEFREE | The 876 Nordic women with PCOS, aged 14-57 years, were examined for T2D and prediabetes (impaired glucose tolerance [IGT] or impaired fasting glucose (IFG) by OGTT. | 29040530 | 2017 | ||||
|
0.060 | GeneticVariation | disease | BEFREE | It is not known whether a similar genetic impact on the risk of prediabetes (impaired glucose tolerance [IGT] or impaired fasting glycemia [IFG]) exists. | 22768041 | 2012 | ||||
|
0.060 | GeneticVariation | disease | BEFREE | In logistic regression analysis, RBP4 levels in the fourth quartile versus the first quartile were significantly associated with prediabetes (i-IGT, i-IFG, and IFG/IGT; reference normal glucose tolerance) independent of known metabolic risk factors and lifestyle variables (odds ratio 1.63 [95% CI 1.17-2.27] after multivariable adjustment). | 21617096 | 2011 |