Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
0.300 Biomarker disease CTD_human Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood. 28696432 2018
Entrez Id: 85458
Gene Symbol: DIXDC1
DIXDC1
0.300 Biomarker disease CTD_human DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling. 27752079 2018
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
0.300 Biomarker disease CTD_human Knockout of alpha 5 nicotinic acetylcholine receptors subunit alters ethanol-mediated behavioral effects and reward in mice. 29944862 2018
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
0.300 Biomarker disease CTD_human Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy. 29860433 2018
Entrez Id: 7038
Gene Symbol: TG
TG
0.300 Biomarker disease CTD_human Hashimoto's thyroiditis induces neuroinflammation and emotional alterations in euthyroid mice. 30373627 2018
Entrez Id: 27185
Gene Symbol: DISC1
DISC1
0.300 Biomarker disease CTD_human DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders. 29643356 2018
Entrez Id: 338811
Gene Symbol: TAFA2
TAFA2
0.300 Biomarker disease CTD_human Targeted knockout of a chemokine-like gene increases anxiety and fear responses. 29339520 2018
Entrez Id: 2332
Gene Symbol: FMR1
FMR1
0.300 Biomarker disease CTD_human Acamprosate in a mouse model of fragile X syndrome: modulation of spontaneous cortical activity, ERK1/2 activation, locomotor behavior, and anxiety. 28616095 2017
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
0.300 Biomarker disease CTD_human Anxiety-like behavior and dysregulation of miR-34a in triple transgenic mice of Alzheimer's disease. 27424985 2016
Entrez Id: 8320
Gene Symbol: EOMES
EOMES
0.300 Biomarker disease CTD_human Ablation of hippocampal neurogenesis in mice impairs the response to stress during the dark cycle. 26415720 2015
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
0.300 Biomarker disease CTD_human S-SCAM, a rare copy number variation gene, induces schizophrenia-related endophenotypes in transgenic mouse model. 25653350 2015
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
0.300 Biomarker disease CTD_human Persistent overexpression of DNA methyltransferase 1 attenuating GABAergic inhibition in basolateral amygdala accounts for anxiety in rat offspring exposed perinatally to low-dose bisphenol A. 23791455 2013
Entrez Id: 1141
Gene Symbol: CHRNB2
CHRNB2
0.300 Biomarker disease CTD_human The β2 nicotinic acetylcholine receptor subunit differentially influences ethanol behavioral effects in the mouse. 23419392 2013
Entrez Id: 2739
Gene Symbol: GLO1
GLO1
0.300 Biomarker disease CTD_human Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. 22113448 2012
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
0.300 Biomarker disease CTD_human Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome. 22231481 2012
Entrez Id: 1392
Gene Symbol: CRH
CRH
0.300 Biomarker disease CTD_human Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome. 22231481 2012
Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
0.300 Biomarker disease CTD_human Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome. 22231481 2012
Entrez Id: 2782
Gene Symbol: GNB1
GNB1
0.300 Biomarker disease CTD_human Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. 22113448 2012
Entrez Id: 594857
Gene Symbol: NPS
NPS
0.300 Therapeutic disease CTD_human Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68). 21466221 2011
Entrez Id: 4282
Gene Symbol: MIF
MIF
0.300 Biomarker disease CTD_human Macrophage migration inhibitory factor is critically involved in basal and fluoxetine-stimulated adult hippocampal cell proliferation and in anxiety, depression, and memory-related behaviors. 20177408 2011
Entrez Id: 594857
Gene Symbol: NPS
NPS
0.300 Biomarker disease CTD_human Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68). 21466221 2011
Entrez Id: 3363
Gene Symbol: HTR7
HTR7
0.300 Biomarker disease CTD_human Optimization of (arylpiperazinylbutyl)oxindoles exhibiting selective 5-HT₇ receptor antagonist activity. 21859099 2011
Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A
0.300 Biomarker disease CTD_human Genetics of caffeine consumption and responses to caffeine. 20532872 2010
Entrez Id: 5066
Gene Symbol: PAM
PAM
0.300 Biomarker disease CTD_human Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. 19815072 2010
Entrez Id: 1392
Gene Symbol: CRH
CRH
0.300 Biomarker disease CTD_human [Selective influence of dehydroepiandrosterone-sulphate on anxiety induced by corticotropin-releasing hormone injection]. 21268831 2010