| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.100 | GeneticVariation | disease | BEFREE | IL1RN gene variants were tested for association with OA progression and for potential interaction with body mass index (BMI). | 23602982 | 2013 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | IL1B -511(G>A) and IL1RN (VNTR) allelic polymorphisms and susceptibility to knee osteoarthritis in Croatian population. | 21523343 | 2012 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis. | 21146623 | 2011 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | Potential influence of interleukin-1 receptor antagonist gene polymorphism on knee osteoarthritis risk. | 20592454 | 2010 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations. | 19934104 | 2010 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | Genetic polymorphisms of interleukin-1beta (-511C/T) and interleukin-1 receptor antagonist (86-bpVNTR) in susceptibility to knee osteoarthritis in a Chinese Han population. | 19151976 | 2009 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | The lack of correlation between the increased frequency of allele IL-1RN*2 of interleukin-1 receptor antagonist gene in Czech patients with knee osteoarthritis and the markers of cartilage degradation. | 18808736 | 2008 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | Extended haplotypes and linkage disequilibrium in the IL1R1-IL1A-IL1B-IL1RN gene cluster: association with knee osteoarthritis. | 15190266 | 2004 | ||||
|
0.100 | Biomarker | disease | LHGDN | Association of the interleukin-1 gene cluster on chromosome 2q13 with knee osteoarthritis. | 12115182 | 2002 | ||||
|
0.100 | Biomarker | disease | BEFREE | This study showed that a local increase in IL-1Ra production in OA knee joints by intraarticular injection of transduced synovial cells can reduce the progression of experimentally induced lesions. | 9182910 | 1997 |