Gene: IL6 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.100 Biomarker disease BEFREE The expressions of vascular cellular adhesion molecule-1 (VCAM-1), intracellular adhesion molecule-1 (ICAM-1), interferon-γ (IFN-γ), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and monocyte chemoattractant protein-1 (MCP-1) in MRL/lpr mouse glomerular endothelial cells (lupus-MGECs) were estimated by quantitative real-time polymerase chain reaction, enzyme-linked immunosorbent assay and Western blotting. 30268079 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.100 Biomarker disease BEFREE IL-1<i>β</i> and IL-6 Are Highly Expressed in RF+IgE+ Systemic Lupus Erythematous Subtype. 28286780 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.100 Biomarker disease BEFREE This study investigated the IL-6-hepcidin-hemoglobin axis in patients with lupus. 27416847 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.100 AlteredExpression disease BEFREE Lupus mice were established by confirming elevated levels of autoantibodies and IL-6 after intraperitoneal injection of pristane. 28303221 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.100 Biomarker disease BEFREE Lupus Skin Is Primed for IL-6 Inflammatory Responses through a Keratinocyte-Mediated Autocrine Type I Interferon Loop. 27646883 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.100 GeneticVariation disease BEFREE Genetic polymorphisms of interleukin 6 and interleukin 10 in Egyptian patients with systemic lupus eythematosus. 26568585 2016
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.100 AlteredExpression disease BEFREE African American women with lupus had significantly higher serum levels of IL-6 and TNF-α. 24865418 2014
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.100 Biomarker disease BEFREE We also measured the IL-6 concentration secreted by peripheral blood mononuclear cells (PBMCs) incubated with (a) oligonucleotide (CpG-B) in the presence or absence of recombinant human PGRN (rhPGRN); and (b) lupus sera in the presence or absence of a neutralizing anti-PGRN antibody. 23140401 2012
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.100 GeneticVariation disease BEFREE The aim of this study is to investigate whether the IL-6 -174 G/C polymorphism associates with lupus susceptibility or affects disease characteristics in Portuguese patients with SLE. 21153673 2011
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.100 AlteredExpression disease BEFREE IL-6 modulates CD5 expression in B cells from patients with lupus by regulating DNA methylation. 19380809 2009