×
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6
0.160
GeneticVariation
disease
BEFREE
Genetic polymorphisms of GPR126 are functionally associated with PUMC classifications of adolescent idiopathic scoliosis in a Northern Han population.
29363878 2018
×
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6
0.160
GeneticVariation
disease
BEFREE
Moreover, GPR126 (ADGRG6 ) mutations are associated with human diseases, like adolescent idiopathic scoliosis , lung disease, bladder cancer, and intellectual disability.
31215653 2019
×
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6
0.160
GeneticVariation
disease
BEFREE
Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis .
23666238 2013
×
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6
0.160
GeneticVariation
disease
BEFREE
A genetic association study of GPR126 gene with adolescent idiopathic scoliosis (AIS) in the Chinese population.
28198779 2017
×
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6
0.160
AlteredExpression
disease
BEFREE
Asymmetric expression of GPR126 in the convex/concave side of the spine is associated with spinal skeletal malformation in adolescent idiopathic scoliosis population.
31079250 2019
×
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6
0.160
Biomarker
disease
BEFREE
The genetic association of GPR126 gene and AIS might provide valuable insights into the pathogenesis of adolescent idiopathic scoliosis .
25479386 2015
×
Entrez Id: 7421
Gene Symbol: VDR
VDR
0.140
GeneticVariation
disease
BEFREE
Association between polymorphisms in vitamin D receptor gene and adolescent idiopathic scoliosis : a meta-analysis.
29728923 2018
×
Entrez Id: 7421
Gene Symbol: VDR
VDR
0.140
GeneticVariation
disease
BEFREE
Correlations of VDR and VDBP genetic polymorphisms with susceptibility to adolescent idiopathic scoliosis and efficacy of brace treatment.
27856225 2016
×
Entrez Id: 7421
Gene Symbol: VDR
VDR
0.140
GeneticVariation
disease
BEFREE
Association of vitamin D receptor BsmI rs1544410 and ApaI rs7975232 polymorphisms with susceptibility to adolescent idiopathic scoliosis : A systematic review and meta-analysis.
29480871 2018
×
Entrez Id: 7421
Gene Symbol: VDR
VDR
0.140
GeneticVariation
disease
BEFREE
Polymorphism in vitamin D receptor is associated with bone mineral density in patients with adolescent idiopathic scoliosis .
20361340 2010
×
Entrez Id: 54796
Gene Symbol: BNC2
BNC2
0.120
GeneticVariation
disease
BEFREE
Genetic variant of BNC2 gene is functionally associated with adolescent idiopathic scoliosis in Chinese population.
28342042 2017
×
Entrez Id: 54796
Gene Symbol: BNC2
BNC2
0.120
Biomarker
disease
BEFREE
An international meta-analysis confirms the association of BNC2 with adolescent idiopathic scoliosis .
29549362 2018
×
Entrez Id: 5077
Gene Symbol: PAX3
PAX3
0.110
AlteredExpression
disease
BEFREE
Abnormal paravertebral muscles development is associated with abnormal expression of PAX3 in adolescent idiopathic scoliosis .
31832874 2020
×
Entrez Id: 28
Gene Symbol: ABO
ABO
0.110
Biomarker
disease
BEFREE
A recent large-scale genome-wide association study reported three novel loci in CDH13, ABO , and SOX6 genes associated with adolescent idiopathic scoliosis (AIS) in Japanese population.
30994600 2019
×
Entrez Id: 10752
Gene Symbol: CHL1
CHL1
0.110
GeneticVariation
disease
BEFREE
Lack of association between the CHL1 gene and adolescent idiopathic scoliosis susceptibility in Han Chinese: a case-control study.
24512353 2014
LBX1-AS1
0.110
GeneticVariation
disease
BEFREE
Previously, we identified an adolescent idiopathic scoliosis susceptibility locus near human ladybird homeobox 1 (LBX1) and FLJ41350 by a genome-wide association study.
26820155 2016
×
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
0.110
Biomarker
disease
BEFREE
A recent large-scale genome-wide association study reported three novel loci in CDH13, ABO, and SOX6 genes associated with adolescent idiopathic scoliosis (AIS) in Japanese population.
30994600 2019
MIR4300HG
0.110
GeneticVariation
disease
BEFREE
A functional variant in MIR4300HG , the host gene of microRNA MIR4300 is associated with progression of adolescent idiopathic scoliosis .
29016859 2017
×
Entrez Id: 10660
Gene Symbol: LBX1
LBX1
0.100
Biomarker
disease
BEFREE
Paraspinal muscle ladybird homeobox 1 (LBX1 ) in adolescent idiopathic scoliosis : a cross-sectional study.
31202838 2019
×
Entrez Id: 10660
Gene Symbol: LBX1
LBX1
0.100
GeneticVariation
disease
BEFREE
SNP rs11190870 near LBX1 is associated with adolescent idiopathic scoliosis in southern Chinese.
22301463 2012
×
Entrez Id: 10660
Gene Symbol: LBX1
LBX1
0.100
GeneticVariation
disease
BEFREE
Association of rs11190870 near LBX1 with adolescent idiopathic scoliosis susceptibility in a Han Chinese population.
23096252 2013
×
Entrez Id: 10660
Gene Symbol: LBX1
LBX1
0.100
GeneticVariation
disease
BEFREE
Association between ladybird homeobox 1 gene polymorphisms and adolescent idiopathic scoliosis : A MOOSE-compliant meta-analysis.
31277174 2019
×
Entrez Id: 10660
Gene Symbol: LBX1
LBX1
0.100
GeneticVariation
disease
BEFREE
Associations of LBX1 gene and adolescent idiopathic scoliosis susceptibility: a meta-analysis based on 34,626 subjects.
27450593 2016
×
Entrez Id: 10660
Gene Symbol: LBX1
LBX1
0.100
GeneticVariation
disease
BEFREE
A meta-analysis identifies adolescent idiopathic scoliosis association with LBX1 locus in multiple ethnic groups.
24721834 2014
×
Entrez Id: 10660
Gene Symbol: LBX1
LBX1
0.100
GeneticVariation
disease
BEFREE
Haplotypes at LBX1 have distinct inheritance patterns with opposite effects in adolescent idiopathic scoliosis .
25675428 2015