Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6 		0.160 GeneticVariation disease BEFREE Moreover, GPR126 (ADGRG6) mutations are associated with human diseases, like adolescent idiopathic scoliosis, lung disease, bladder cancer, and intellectual disability. 31215653 2019
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6 		0.160 AlteredExpression disease BEFREE Asymmetric expression of GPR126 in the convex/concave side of the spine is associated with spinal skeletal malformation in adolescent idiopathic scoliosis population. 31079250 2019
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6 		0.160 GeneticVariation disease GWASCAT Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese. 31417091 2019
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6 		0.160 GeneticVariation disease BEFREE Genetic polymorphisms of GPR126 are functionally associated with PUMC classifications of adolescent idiopathic scoliosis in a Northern Han population. 29363878 2018
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6 		0.160 GeneticVariation disease GWASCAT Genome-wide meta-analysis and replication studies in multiple ethnicities identify novel adolescent idiopathic scoliosis susceptibility loci. 30395268 2018
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6 		0.160 GeneticVariation disease BEFREE A genetic association study of GPR126 gene with adolescent idiopathic scoliosis (AIS) in the Chinese population. 28198779 2017
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6 		0.160 Biomarker disease BEFREE The genetic association of GPR126 gene and AIS might provide valuable insights into the pathogenesis of adolescent idiopathic scoliosis. 25479386 2015
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6 		0.160 GeneticVariation disease GWASDB Identification of a susceptibility locus for severe adolescent idiopathic scoliosis on chromosome 17q24.3. 24023777 2013
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6 		0.160 GeneticVariation disease BEFREE Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis. 23666238 2013
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.140 GeneticVariation disease BEFREE Association between polymorphisms in vitamin D receptor gene and adolescent idiopathic scoliosis: a meta-analysis. 29728923 2018
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.140 GeneticVariation disease BEFREE Association of vitamin D receptor BsmI rs1544410 and ApaI rs7975232 polymorphisms with susceptibility to adolescent idiopathic scoliosis: A systematic review and meta-analysis. 29480871 2018
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.140 GeneticVariation disease GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.140 GeneticVariation disease BEFREE Correlations of VDR and VDBP genetic polymorphisms with susceptibility to adolescent idiopathic scoliosis and efficacy of brace treatment. 27856225 2016
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.140 GeneticVariation disease BEFREE Polymorphism in vitamin D receptor is associated with bone mineral density in patients with adolescent idiopathic scoliosis. 20361340 2010
Entrez Id: 54796
Gene Symbol: BNC2
BNC2 		0.120 GeneticVariation disease GWASCAT Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese. 31417091 2019
Entrez Id: 54796
Gene Symbol: BNC2
BNC2 		0.120 GeneticVariation disease GWASCAT Genome-wide meta-analysis and replication studies in multiple ethnicities identify novel adolescent idiopathic scoliosis susceptibility loci. 30395268 2018
Entrez Id: 54796
Gene Symbol: BNC2
BNC2 		0.120 Biomarker disease BEFREE An international meta-analysis confirms the association of BNC2 with adolescent idiopathic scoliosis. 29549362 2018
Entrez Id: 54796
Gene Symbol: BNC2
BNC2 		0.120 GeneticVariation disease BEFREE Genetic variant of BNC2 gene is functionally associated with adolescent idiopathic scoliosis in Chinese population. 28342042 2017
Entrez Id: 54796
Gene Symbol: BNC2
BNC2 		0.120 GeneticVariation disease GWASCAT A Functional SNP in BNC2 Is Associated with Adolescent Idiopathic Scoliosis. 26211971 2015
Entrez Id: 5077
Gene Symbol: PAX3
PAX3 		0.110 AlteredExpression disease BEFREE Abnormal paravertebral muscles development is associated with abnormal expression of PAX3 in adolescent idiopathic scoliosis. 31832874 2020
Entrez Id: 28
Gene Symbol: ABO
ABO 		0.110 Biomarker disease BEFREE A recent large-scale genome-wide association study reported three novel loci in CDH13, ABO, and SOX6 genes associated with adolescent idiopathic scoliosis (AIS) in Japanese population. 30994600 2019
Entrez Id: 55553
Gene Symbol: SOX6
SOX6 		0.110 Biomarker disease BEFREE A recent large-scale genome-wide association study reported three novel loci in CDH13, ABO, and SOX6 genes associated with adolescent idiopathic scoliosis (AIS) in Japanese population. 30994600 2019
Entrez Id: 5077
Gene Symbol: PAX3
PAX3 		0.110 GeneticVariation disease GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
Entrez Id: 55553
Gene Symbol: SOX6
SOX6 		0.110 GeneticVariation disease GWASCAT Genome-wide meta-analysis and replication studies in multiple ethnicities identify novel adolescent idiopathic scoliosis susceptibility loci. 30395268 2018
Entrez Id: 10752
Gene Symbol: CHL1
CHL1 		0.110 GeneticVariation disease GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018