Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 590
Gene Symbol: BCHE
BCHE 		0.300 Therapeutic phenotype CTD_human Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine. 20971807 2011
Entrez Id: 5443
Gene Symbol: POMC
POMC 		0.300 Therapeutic phenotype CTD_human Systemic morphine blocks the seizures induced by intracerebroventricular (i.c.v.) injections of opiates and opioid peptides. 7127082 1982
Entrez Id: 5978
Gene Symbol: REST
REST 		0.300 Therapeutic phenotype CTD_human Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy. 21905079 2011
Entrez Id: 5020
Gene Symbol: OXT
OXT 		0.300 Biomarker phenotype CTD_human A generalized epileptiform convulsion after intra-amniotic prostaglandin with intravenous oxytocin infusion: a case report. 644406 1978
Entrez Id: 5173
Gene Symbol: PDYN
PDYN 		0.300 Therapeutic phenotype CTD_human [The role of the opiate mechanisms of the hippocampus and substantia nigra in the behavioral and convulsive disorders in picrotoxin-induced kindling]. 1675896 1991
Entrez Id: 2897
Gene Symbol: GRIK1
GRIK1 		0.300 Biomarker phenotype CTD_human Antagonists of GLU(K5)-containing kainate receptors prevent pilocarpine-induced limbic seizures. 12080343 2002
Entrez Id: 590
Gene Symbol: BCHE
BCHE 		0.300 Therapeutic phenotype CTD_human Administration of purified human plasma cholinesterase protects against cocaine toxicity in mice. 8667461 1996
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.300 Biomarker phenotype CTD_human Involvement of the somatostatin-2 receptor in the anti-convulsant effect of angiotensin IV against pilocarpine-induced limbic seizures in rats. 16771832 2006
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7 		0.300 Biomarker phenotype CTD_human Pharmacological characterization of nicotine-induced seizures in mice. 10565853 1999
Entrez Id: 5020
Gene Symbol: OXT
OXT 		0.300 Biomarker phenotype CTD_human Water intoxication and Syntocinon infusion. 292422 1979
Entrez Id: 7248
Gene Symbol: TSC1
TSC1 		0.300 Biomarker phenotype CTD_human Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia. 28215400 2017
Entrez Id: 1143
Gene Symbol: CHRNB4
CHRNB4 		0.300 Biomarker phenotype CTD_human Mice lacking neuronal nicotinic acetylcholine receptor beta4-subunit and mice lacking both alpha5- and beta4-subunits are highly resistant to nicotine-induced seizures. 14996991 2004
Entrez Id: 4852
Gene Symbol: NPY
NPY 		0.300 Biomarker phenotype CTD_human Seizure susceptibility of neuropeptide-Y null mutant mice in amygdala kindling and chemical-induced seizure models. 15451008 2004
Entrez Id: 54805
Gene Symbol: CNNM2
CNNM2 		0.300 Biomarker phenotype CTD_human Purification, crystallization and preliminary crystallographic analysis of the CBS-domain pair of cyclin M2 (CNNM2). 23027747 2012
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.300 Therapeutic phenotype CTD_human Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus. 21269288 2011
Entrez Id: 6925
Gene Symbol: TCF4
TCF4 		0.300 Biomarker phenotype CTD_human Further delineation of Pitt-Hopkins syndrome: phenotypic and genotypic description of 16 novel patients. 18728071 2008
Entrez Id: 4803
Gene Symbol: NGF
NGF 		0.300 Biomarker phenotype CTD_human Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures. 18815271 2008
Entrez Id: 7200
Gene Symbol: TRH
TRH 		0.300 Biomarker phenotype CTD_human Effects of pilocarpine- and kainate-induced seizures on thyrotropin-releasing hormone biosynthesis and receptors in the rat brain. 10443546 1999
Entrez Id: 6547
Gene Symbol: SLC8A3
SLC8A3 		0.300 Biomarker phenotype CTD_human Blockade of the sodium calcium exchanger exhibits anticonvulsant activity in a pilocarpine model of acute seizures in rats. 20888801 2010
Entrez Id: 54886
Gene Symbol: PLPPR1
PLPPR1 		0.300 Biomarker phenotype CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1 		0.300 Biomarker phenotype CTD_human Mutational analysis of GLUT1 (SLC2A1) in Glut-1 deficiency syndrome. 10980529 2000
Entrez Id: 2572
Gene Symbol: GAD2
GAD2 		0.300 Biomarker phenotype CTD_human Mice lacking the 65 kDa isoform of glutamic acid decarboxylase (GAD65) maintain normal levels of GAD67 and GABA in their brains but are susceptible to seizures. 8954991 1996
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7 		0.300 Biomarker phenotype CTD_human Sensitivity to the seizure-inducing effects of nicotine is associated with strain-specific variants of the alpha 5 and alpha 7 nicotinic receptor subunit genes. 9495872 1998
Entrez Id: 249
Gene Symbol: ALPL
ALPL 		0.300 Biomarker phenotype CTD_human Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation. 27466191 2016
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2 		0.300 Biomarker phenotype CTD_human Genetic deletion of the norepinephrine transporter decreases vulnerability to seizures. 15911120 2005