Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.300 Therapeutic phenotype CTD_human Cardiac hypertrophy associated with ACTH therapy for childhood seizure disorder. 2821097 1987
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.300 Biomarker phenotype CTD_human Cardiac hypertrophy associated with ACTH therapy for childhood seizure disorder. 2821097 1987
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.300 Biomarker phenotype CTD_human Changes in brain interleukin-1beta following the coadministration of norfloxacin with biphenylacetic acid in rats. 16824509 2006
Entrez Id: 2353
Gene Symbol: FOS
FOS
0.300 Biomarker phenotype CTD_human Continuous administration of antisense oligonucleotides to c-fos reduced the development of seizure susceptibility after ethacrynic acid-induced seizure in mice. 12946577 2003
Entrez Id: 1392
Gene Symbol: CRH
CRH
0.300 Biomarker phenotype CTD_human Corticotropin-releasing hormone is a rapid and potent convulsant in the infant rat. 1914160 1991
Entrez Id: 1392
Gene Symbol: CRH
CRH
0.300 Biomarker phenotype CTD_human Corticotropin-releasing hormone-induced seizures in infant rats originate in the amygdala. 1596084 1992
Entrez Id: 3737
Gene Symbol: KCNA2
KCNA2
0.300 Biomarker phenotype CTD_human De novo loss- or gain-of-function mutations in KCNA2 cause epileptic encephalopathy. 25751627 2015
Entrez Id: 8828
Gene Symbol: NRP2
NRP2
0.300 Biomarker phenotype CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
Entrez Id: 590
Gene Symbol: BCHE
BCHE
0.300 Therapeutic phenotype CTD_human Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine. 20971807 2011
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.300 Therapeutic phenotype CTD_human Differential effects of vigabatrin and zonisamide on the neuropeptide Y system in the hippocampus of seizure prone gerbil. 16194568 2005
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.300 Biomarker phenotype CTD_human Differential effects of vigabatrin and zonisamide on the neuropeptide Y system in the hippocampus of seizure prone gerbil. 16194568 2005
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.300 Therapeutic phenotype CTD_human Dopamine D1 and D2 receptors mediate opposite functions in seizures induced by lithium-pilocarpine. 1829682 1991
Entrez Id: 1812
Gene Symbol: DRD1
DRD1
0.300 Biomarker phenotype CTD_human Dopamine D1 and D2 receptors mediate opposite functions in seizures induced by lithium-pilocarpine. 1829682 1991
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.300 Biomarker phenotype CTD_human Dopamine D1 and D2 receptors mediate opposite functions in seizures induced by lithium-pilocarpine. 1829682 1991
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.300 Biomarker phenotype CTD_human Dopamine D2 receptor signaling controls neuronal cell death induced by muscarinic and glutamatergic drugs. 11860278 2002
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.300 Therapeutic phenotype CTD_human Dopamine D2 receptor signaling controls neuronal cell death induced by muscarinic and glutamatergic drugs. 11860278 2002
Entrez Id: 1812
Gene Symbol: DRD1
DRD1
0.300 Biomarker phenotype CTD_human Dopaminergic modulation of pilocarpine-induced motor seizures in the rat: the role of hippocampal dopamine D1 receptors. 1451735 1992
Entrez Id: 3630
Gene Symbol: INS
INS
0.300 Biomarker phenotype CTD_human Drug-induced convulsions. Report from Boston Collaborative Drug Surveillance Program. 4115818 1972
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.300 Biomarker phenotype CTD_human Effects of dopamine D3 receptor agonists on pilocarpine-induced limbic seizures in the rat. 7936204 1994
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.300 Therapeutic phenotype CTD_human Effects of dopamine D3 receptor agonists on pilocarpine-induced limbic seizures in the rat. 7936204 1994
Entrez Id: 7200
Gene Symbol: TRH
TRH
0.300 Biomarker phenotype CTD_human Effects of pilocarpine- and kainate-induced seizures on thyrotropin-releasing hormone biosynthesis and receptors in the rat brain. 10443546 1999
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.300 Therapeutic phenotype CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040 2005
Entrez Id: 7200
Gene Symbol: TRH
TRH
0.300 Biomarker phenotype CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040 2005
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.300 Biomarker phenotype CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040 2005
Entrez Id: 590
Gene Symbol: BCHE
BCHE
0.300 Therapeutic phenotype CTD_human Efficacy of human serum butyrylcholinesterase against sarin vapor. 18597747 2008