Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4986
Gene Symbol: OPRK1
OPRK1
0.300 Therapeutic phenotype CTD_human Mechanisms of morphine enhancement of spontaneous seizure activity. 18042875 2007
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.300 Therapeutic phenotype CTD_human Sigma 1 receptor-mediated increase in hippocampal extracellular dopamine contributes to the mechanism of the anticonvulsant action of neuropeptide Y. 18005069 2007
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.300 Biomarker phenotype CTD_human Sigma 1 receptor-mediated increase in hippocampal extracellular dopamine contributes to the mechanism of the anticonvulsant action of neuropeptide Y. 18005069 2007
Entrez Id: 183
Gene Symbol: AGT
AGT
0.300 Biomarker phenotype CTD_human Involvement of the somatostatin-2 receptor in the anti-convulsant effect of angiotensin IV against pilocarpine-induced limbic seizures in rats. 16771832 2006
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2
0.300 Biomarker phenotype CTD_human Expression of the multidrug transporter MRP2 in the blood-brain barrier after pilocarpine-induced seizures in rats. 16504477 2006
Entrez Id: 6752
Gene Symbol: SSTR2
SSTR2
0.300 Therapeutic phenotype CTD_human Involvement of the somatostatin-2 receptor in the anti-convulsant effect of angiotensin IV against pilocarpine-induced limbic seizures in rats. 16771832 2006
Entrez Id: 6750
Gene Symbol: SST
SST
0.300 Therapeutic phenotype CTD_human Involvement of the somatostatin-2 receptor in the anti-convulsant effect of angiotensin IV against pilocarpine-induced limbic seizures in rats. 16771832 2006
Entrez Id: 6750
Gene Symbol: SST
SST
0.300 Biomarker phenotype CTD_human Involvement of the somatostatin-2 receptor in the anti-convulsant effect of angiotensin IV against pilocarpine-induced limbic seizures in rats. 16771832 2006
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.300 Biomarker phenotype CTD_human Changes in brain interleukin-1beta following the coadministration of norfloxacin with biphenylacetic acid in rats. 16824509 2006
Entrez Id: 93183
Gene Symbol: PIGM
PIGM
0.300 Biomarker phenotype CTD_human Hypomorphic promoter mutation in PIGM causes inherited glycosylphosphatidylinositol deficiency. 16767100 2006
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2
0.300 Biomarker phenotype CTD_human Genetic deletion of the norepinephrine transporter decreases vulnerability to seizures. 15911120 2005
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
0.300 Biomarker phenotype CTD_human Stimulation of 5-HT 1A receptors increases the seizure threshold for picrotoxin in mice. 16313900 2005
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.300 Therapeutic phenotype CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040 2005
Entrez Id: 7200
Gene Symbol: TRH
TRH
0.300 Biomarker phenotype CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040 2005
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.300 Therapeutic phenotype CTD_human Differential effects of vigabatrin and zonisamide on the neuropeptide Y system in the hippocampus of seizure prone gerbil. 16194568 2005
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.300 Biomarker phenotype CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040 2005
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.300 Biomarker phenotype CTD_human Differential effects of vigabatrin and zonisamide on the neuropeptide Y system in the hippocampus of seizure prone gerbil. 16194568 2005
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
0.300 Therapeutic phenotype CTD_human Stimulation of 5-HT 1A receptors increases the seizure threshold for picrotoxin in mice. 16313900 2005
Entrez Id: 1137
Gene Symbol: CHRNA4
CHRNA4
0.300 Biomarker phenotype CTD_human Novel seizure phenotype and sleep disruptions in knock-in mice with hypersensitive alpha 4* nicotinic receptors. 16339034 2005
Entrez Id: 2593
Gene Symbol: GAMT
GAMT
0.300 Biomarker phenotype CTD_human Guanidinoacetate methyltransferase deficiency identified in adults and a child with mental retardation. 15651030 2005
Entrez Id: 1143
Gene Symbol: CHRNB4
CHRNB4
0.300 Biomarker phenotype CTD_human Mice lacking neuronal nicotinic acetylcholine receptor beta4-subunit and mice lacking both alpha5- and beta4-subunits are highly resistant to nicotine-induced seizures. 14996991 2004
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.300 Biomarker phenotype CTD_human Seizure susceptibility of neuropeptide-Y null mutant mice in amygdala kindling and chemical-induced seizure models. 15451008 2004
Entrez Id: 3954
Gene Symbol: LETM1
LETM1
0.300 Biomarker phenotype CTD_human LETM1, a gene deleted in Wolf-Hirschhorn syndrome, encodes an evolutionarily conserved mitochondrial protein. 14706454 2004
Entrez Id: 1143
Gene Symbol: CHRNB4
CHRNB4
0.300 Biomarker phenotype CTD_human The alpha3 and beta4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice. 15275829 2004
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.300 Therapeutic phenotype CTD_human Seizure susceptibility of neuropeptide-Y null mutant mice in amygdala kindling and chemical-induced seizure models. 15451008 2004