Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 116
Gene Symbol: ADCYAP1
ADCYAP1
0.300 Biomarker phenotype CTD_human IL-6 knockout mice are protected from cocaine-induced kindling behaviors; possible involvement of JAK2/STAT3 and PACAP signalings. 29673861 2018
Entrez Id: 7248
Gene Symbol: TSC1
TSC1
0.300 Biomarker phenotype CTD_human Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia. 28215400 2017
Entrez Id: 7249
Gene Symbol: TSC2
TSC2
0.300 Biomarker phenotype CTD_human Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia. 28215400 2017
Entrez Id: 249
Gene Symbol: ALPL
ALPL
0.300 Therapeutic phenotype CTD_human Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation. 27466191 2016
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
0.300 Biomarker phenotype CTD_human Protein kinase Cδ mediates trimethyltin-induced neurotoxicity in mice in vivo via inhibition of glutathione defense mechanism. 25895139 2016
Entrez Id: 43
Gene Symbol: ACHE
ACHE
0.300 Therapeutic phenotype CTD_human HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants. 27083141 2016
Entrez Id: 43
Gene Symbol: ACHE
ACHE
0.300 Biomarker phenotype CTD_human HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants. 27083141 2016
Entrez Id: 249
Gene Symbol: ALPL
ALPL
0.300 Biomarker phenotype CTD_human Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation. 27466191 2016
Entrez Id: 3785
Gene Symbol: KCNQ2
KCNQ2
0.300 Biomarker phenotype CTD_human KCNQ2 encephalopathy: Features, mutational hot spots, and ezogabine treatment of 11 patients. 27602407 2016
Entrez Id: 6904
Gene Symbol: TBCD
TBCD
0.300 Biomarker phenotype CTD_human Biallelic Mutations in TBCD, Encoding the Tubulin Folding Cofactor D, Perturb Microtubule Dynamics and Cause Early-Onset Encephalopathy. 27666370 2016
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
0.300 Biomarker phenotype CTD_human A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model. 27469509 2016
Entrez Id: 2166
Gene Symbol: FAAH
FAAH
0.300 Therapeutic phenotype CTD_human Enhancement of endocannabinoid signaling protects against cocaine-induced neurotoxicity. 25933444 2015
Entrez Id: 3737
Gene Symbol: KCNA2
KCNA2
0.300 Biomarker phenotype CTD_human De novo loss- or gain-of-function mutations in KCNA2 cause epileptic encephalopathy. 25751627 2015
Entrez Id: 6505
Gene Symbol: SLC1A1
SLC1A1
0.300 Biomarker phenotype CTD_human Caffeine-induced inhibition of the activity of glutamate transporter type 3 expressed in Xenopus oocytes. 23262392 2013
Entrez Id: 7779
Gene Symbol: SLC30A1
SLC30A1
0.300 Biomarker phenotype CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 54886
Gene Symbol: PLPPR1
PLPPR1
0.300 Biomarker phenotype CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 Biomarker phenotype CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 38
Gene Symbol: ACAT1
ACAT1
0.300 Biomarker phenotype CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 4504
Gene Symbol: MT3
MT3
0.300 Biomarker phenotype CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 1191
Gene Symbol: CLU
CLU
0.300 Biomarker phenotype CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
0.300 Biomarker phenotype CTD_human Prenatal treatment of mosaic mice (Atp7a mo-ms) mouse model for Menkes disease, with copper combined by dimethyldithiocarbamate (DMDTC). 22815746 2012
Entrez Id: 54805
Gene Symbol: CNNM2
CNNM2
0.300 Biomarker phenotype CTD_human Purification, crystallization and preliminary crystallographic analysis of the CBS-domain pair of cyclin M2 (CNNM2). 23027747 2012
Entrez Id: 6792
Gene Symbol: CDKL5
CDKL5
0.300 Biomarker phenotype CTD_human Historic, clinical, and prognostic features of epileptic encephalopathies caused by CDKL5 mutations. 22264704 2012
Entrez Id: 847
Gene Symbol: CAT
CAT
0.300 Therapeutic phenotype CTD_human Acute seizure activity promotes lipid peroxidation, increased nitrite levels and adaptive pathways against oxidative stress in the frontal cortex and striatum. 20592767 2011
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.300 Therapeutic phenotype CTD_human Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus. 21269288 2011