Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 776
Gene Symbol: CACNA1D
CACNA1D
0.400 Biomarker phenotype CTD_human G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block. 26831068 2016
Entrez Id: 776
Gene Symbol: CACNA1D
CACNA1D
0.400 Biomarker phenotype HPO
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.300 Biomarker phenotype CTD_human [Relationship of blood aryl hydrocarbon receptor mRNA and cytochrome P450 1A1 mRNA expression with corrected QT interval among residents exposed to arsenic via drinking water]. 26988683 2016
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.300 Biomarker phenotype CTD_human [Case of west syndrome associated with transient marked sinus dysfunction during ACTH therapy]. 19039989 2009
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
0.300 Biomarker phenotype CTD_human Cytochrome oxidase 2D6 gene polymorphism in primary open-angle glaucoma with various effects to ophthalmic timolol. 19284319 2009
Entrez Id: 134
Gene Symbol: ADORA1
ADORA1
0.300 Biomarker phenotype CTD_human Hypotensive effects of intravenously administered uridine and cytidine in conscious rats: involvement of adenosine receptors. 18313046 2008
Entrez Id: 2771
Gene Symbol: GNAI2
GNAI2
0.300 Biomarker phenotype CTD_human Endogenous RGS proteins modulate SA and AV nodal functions in isolated heart: implications for sick sinus syndrome and AV block. 17277016 2007
Entrez Id: 10911
Gene Symbol: UTS2
UTS2
0.300 Biomarker phenotype CTD_human Behavioral effects of urotensin-II centrally administered in mice. 16160878 2006
Entrez Id: 11188
Gene Symbol: NISCH
NISCH
0.300 Biomarker phenotype CTD_human Evidence for the involvement of central I1 imidazoline receptor in ethanol counteraction of clonidine hypotension in spontaneously hypertensive rats. 11486246 2001
Entrez Id: 1129
Gene Symbol: CHRM2
CHRM2
0.300 Biomarker phenotype CTD_human Low-affinity M(2) receptor binding state mediates mouse atrial bradycardia: comparative effects of carbamylcholine and the M(1) receptor agonists sabcomeline and xanomeline. 11181912 2001
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.300 Biomarker phenotype CTD_human Cardiovascular responses to intrathecal dopamine receptor agonists in conscious DOCA-salt hypertensive rats. 10626749 2000
Entrez Id: 6869
Gene Symbol: TACR1
TACR1
0.300 Therapeutic phenotype CTD_human Comparison of cardiorespiratory reflexes in NK1 receptor knockout, heterozygous and wild-type mice in vivo. 9696263 1998
Entrez Id: 2641
Gene Symbol: GCG
GCG
0.300 Therapeutic phenotype CTD_human A potential role for glucagon in the treatment of drug-induced symptomatic bradycardia. 9674488 1998
Entrez Id: 183
Gene Symbol: AGT
AGT
0.300 Therapeutic phenotype CTD_human Participation of AT1 and AT2 receptor subtypes in the tonic inhibitory modulation of baroreceptor reflex response by endogenous angiotensins at the nucleus tractus solitarii in the rat. 9519251 1998
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
0.300 Biomarker phenotype CTD_human Facilitation by substance P and inhibition by (+)-tubocurarine of the 5-HT3 receptor-mediated Bezold-Jarisch reflex in rats. 8960879 1997
Entrez Id: 2641
Gene Symbol: GCG
GCG
0.300 Therapeutic phenotype CTD_human Sotalol-induced bradycardia reversed by glucagon. 7787496 1995
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
0.300 Biomarker phenotype CTD_human Mechanism of pain induced by radiocontrast media. 1281941 1993
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
0.300 Therapeutic phenotype CTD_human Endothelin antagonizes the hypotension and potentiates the hypertension induced by clonidine. 8440307 1993
Entrez Id: 1907
Gene Symbol: EDN2
EDN2
0.300 Therapeutic phenotype CTD_human Evidence for antagonistic activity of endothelin for clonidine induced hypotension and bradycardia. 1309933 1992
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.300 Biomarker phenotype CTD_human Hypotensive and bradycardic effects elicited by spinal dopamine receptor stimulation: effects of D1 and D2 receptor agonists and antagonists. 1724532 1992
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
0.300 Therapeutic phenotype CTD_human Evidence for antagonistic activity of endothelin for clonidine induced hypotension and bradycardia. 1309933 1992
Entrez Id: 1908
Gene Symbol: EDN3
EDN3
0.300 Therapeutic phenotype CTD_human Evidence for antagonistic activity of endothelin for clonidine induced hypotension and bradycardia. 1309933 1992
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.300 Biomarker phenotype CTD_human Effects of dynorphin A(1-13) and of fragments of beta-endorphin on blood pressure and heart rate of anesthetized rats. 1676337 1991
Entrez Id: 5173
Gene Symbol: PDYN
PDYN
0.300 Biomarker phenotype CTD_human Effects of dynorphin A(1-13) and of fragments of beta-endorphin on blood pressure and heart rate of anesthetized rats. 1676337 1991
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
0.300 Biomarker phenotype CTD_human Evidence that central 5-HT1A-receptors play a role in the von Bezold-Jarisch reflex in the rat. 2207497 1990