Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.390 | Biomarker | disease | BEFREE | Gene expression was examined to reveal the molecular mechanism underlying the roles of EZH2 in endometrial cancer. | 31640461 | 2020 | ||||
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0.390 | AlteredExpression | disease | BEFREE | We investigated patterns of EZH2 expression in endometrial cancer. | 31843273 | 2020 | ||||
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0.390 | Biomarker | disease | BEFREE | Additionally, small interfering RNA was used to investigate the role of EZH2 in endometrial carcinoma cell proliferation, and the results showed that EZH2 knockdown suppressed the proliferation of endometrial carcinoma cells <i>in vitro</i>. | 29805666 | 2018 | ||||
|
0.390 | Biomarker | disease | BEFREE | This study aimed to investigate the effect of miR-101-3p on autophagy in endometrial carcinoma (EC) cells and the connection between miR-101-3p and EZH2. | 29691644 | 2018 | ||||
|
0.390 | AlteredExpression | disease | BEFREE | Endometrial carcinoma RL-952 cells were transfected with chemically synthesized siRNA to conduct targeting inhibition of EZH2 expression. | 29344151 | 2017 | ||||
|
0.390 | Biomarker | disease | BEFREE | Our findings suggest that EZH2 drives EC progression by regulating miR-361/Twist signaling, and support EZH2 inhibition as a promising anti-EC therapeutic strategy. | 28088786 | 2017 | ||||
|
0.390 | Biomarker | disease | BEFREE | Further studies should explore the therapeutic potential of inhibiting EZH2 in patients with endometrial cancer. | 28418882 | 2017 | ||||
|
0.390 | Biomarker | disease | BEFREE | The microRNA-101-EZH2/MCL-1/FOS axis is a potential therapeutic target for endometrial cancer. | 25153722 | 2014 | ||||
|
0.390 | AlteredExpression | disease | BEFREE | Enhancer of zeste homolog 2 protein expression was increased in all 3 cancer cell lines and human endometrial cancer tissue specimens relative to control. | 23792601 | 2013 | ||||
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0.390 | Biomarker | disease | CTD_human | Down-regulation of the histone methyltransferase EZH2 contributes to the epigenetic programming of decidualizing human endometrial stromal cells. | 21903722 | 2011 |