Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
0.370 Biomarker disease BEFREE However, it is not known how insulin receptor isoform A (IR-A) and insulin-like growth factor 1 receptor (IGF-1R), cognate receptors for insulin and IGFs, respectively, regulate malignant behaviors of EC. 30426831 2019
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
0.370 Biomarker disease BEFREE Taken together, the results of the current study demonstrated that miR-424 was a tumor suppressor for endometrial carcinoma and a favorable factor against tumor progression through targeting IGF-1R, thus providing a target for the treatment of endometrial carcinoma. 30187960 2018
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
0.370 AlteredExpression disease BEFREE This study identifies NEDD4 as a putative oncogene in endometrial cancer that may augment activation of the IGF-1R/PI3K/Akt signaling pathway. 26193427 2015
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
0.370 Biomarker disease BEFREE These findings indicate that specific inhibition of IGF1R could be a useful therapeutic approach for Type 1 and Type 2 endometrial cancer. 23402816 2013
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
0.370 Biomarker disease CTD_human Down-regulation of IGF-1R expression inhibits growth and enhances chemosensitivity of endometrial carcinoma in vitro. 21442237 2011
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
0.370 Biomarker disease BEFREE Thus, manipulation of the IGF-1-R pathway may serve as a promising therapeutic strategy for the treatment of endometrial cancer. 21846689 2011
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
0.370 AlteredExpression disease BEFREE Insulin-like growth factor-I receptor and PTEN protein expression in endometrial carcinoma. Correlation with bax and bcl-2 expression, microsatellite instability status, and outcome. 12866376 2003
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
0.370 AlteredExpression disease BEFREE The IGF-IR and IIR mRNA levels were elevated in endometrial carcinoma samples. 10459850 1999