Gene: APC ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 324
Gene Symbol: APC
APC 		0.030 GeneticVariation disease BEFREE On WES analysis, primary carcinoma with desmoplastic liver metastasis showed mutations in APC (4/5); TP53 (3/5); KRAS, PIK3CA, and FAT4 (2/5); BRCA-1, BRCA2, BRAF, and DNAH5 (1/5), whereas primary carcinoma with replacement liver metastasis showed mutations in APC and TP53 (3/5); KRAS, FAT4, DNH5, SMAD, ERBB2, ERBB3, LRP1, and SDK1 (1/5). 31341365 2019
Entrez Id: 324
Gene Symbol: APC
APC 		0.030 GeneticVariation disease BEFREE All HCC samples and ten patients with liver metastasis (52.6%) exhibited APC promoter methylation. 17973119 2008
Entrez Id: 324
Gene Symbol: APC
APC 		0.030 PosttranslationalModification disease BEFREE Promoter methylation of the APC gene was found to be a frequent event in liver metastasis (10/24) and significantly more frequent compared with primary colorectal cancer (7/39, P = 0.047). 15375009 2005