Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
0.080 Biomarker disease BEFREE Circulating Levels of Osteopontin Predict Patients' Outcome after Resection of Colorectal Liver Metastases. 30373147 2018
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
0.080 Biomarker disease BEFREE The role of OPN in liver metastasis was studied in established colon cancer Colo-205 and SW-480 cell lines transfected with sense- or antisense-OPN eukaryotic expression plasmids by flow cytometry and cell adhesion assay. 23112867 2012
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
0.080 Biomarker disease BEFREE Osteopontin (OPN) is a small integrin-binding N-linked glycoprotein, which plays a crucial role in the formation of hepatic metastasis. 21852811 2011
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
0.080 AlteredExpression disease BEFREE Expression of osteopontin coregulators in primary colorectal cancer and associated liver metastases. 21343932 2011
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
0.080 Biomarker disease BEFREE Finally, the ability of anti-OPN Ab to suppress liver metastasis was investigated. 20339989 2010
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
0.080 AlteredExpression disease BEFREE OPN expression was strongly elevated in primary colon cancer and liver metastasis, but not in pre-cancerous lesions and UICC stage I tumors. 17565744 2007
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
0.080 AlteredExpression disease BEFREE The median plasma OPN level was significantly higher in patients than in controls (p<0.0001), and significantly higher in patients with advanced stages, serosal invasion, lymph node metastasis, lymphatic invasion, venous invasion and liver metastasis. 17148500 2007
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
0.080 Biomarker disease BEFREE Immunohistochemical analysis demonstrated OPN staining in 60% of the primary pancreatic tumors and in 72% of the lymph node and liver metastases. 15970685 2005