Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7249
Gene Symbol: TSC2
TSC2 		0.300 Biomarker disease CTD_human Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia. 28215400 2017
Entrez Id: 249
Gene Symbol: ALPL
ALPL 		0.300 Therapeutic disease CTD_human Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation. 27466191 2016
Entrez Id: 43
Gene Symbol: ACHE
ACHE 		0.300 Biomarker disease CTD_human HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants. 27083141 2016
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD 		0.300 Biomarker disease CTD_human Protein kinase Cδ mediates trimethyltin-induced neurotoxicity in mice in vivo via inhibition of glutathione defense mechanism. 25895139 2016
Entrez Id: 43
Gene Symbol: ACHE
ACHE 		0.300 Therapeutic disease CTD_human HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants. 27083141 2016
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.300 Biomarker disease CTD_human A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model. 27469509 2016
Entrez Id: 249
Gene Symbol: ALPL
ALPL 		0.300 Biomarker disease CTD_human Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation. 27466191 2016
Entrez Id: 2166
Gene Symbol: FAAH
FAAH 		0.300 Therapeutic disease CTD_human Enhancement of endocannabinoid signaling protects against cocaine-induced neurotoxicity. 25933444 2015
Entrez Id: 38
Gene Symbol: ACAT1
ACAT1 		0.300 Biomarker disease CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 1191
Gene Symbol: CLU
CLU 		0.300 Biomarker disease CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 54886
Gene Symbol: PLPPR1
PLPPR1 		0.300 Biomarker disease CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 4504
Gene Symbol: MT3
MT3 		0.300 Biomarker disease CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 6505
Gene Symbol: SLC1A1
SLC1A1 		0.300 Biomarker disease CTD_human Caffeine-induced inhibition of the activity of glutamate transporter type 3 expressed in Xenopus oocytes. 23262392 2013
Entrez Id: 7779
Gene Symbol: SLC30A1
SLC30A1 		0.300 Biomarker disease CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A 		0.300 Biomarker disease CTD_human Prenatal treatment of mosaic mice (Atp7a mo-ms) mouse model for Menkes disease, with copper combined by dimethyldithiocarbamate (DMDTC). 22815746 2012
Entrez Id: 54805
Gene Symbol: CNNM2
CNNM2 		0.300 Biomarker disease CTD_human Purification, crystallization and preliminary crystallographic analysis of the CBS-domain pair of cyclin M2 (CNNM2). 23027747 2012
Entrez Id: 847
Gene Symbol: CAT
CAT 		0.300 Biomarker disease CTD_human Acute seizure activity promotes lipid peroxidation, increased nitrite levels and adaptive pathways against oxidative stress in the frontal cortex and striatum. 20592767 2011
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.300 Therapeutic disease CTD_human Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus. 21269288 2011
Entrez Id: 847
Gene Symbol: CAT
CAT 		0.300 Therapeutic disease CTD_human Acute seizure activity promotes lipid peroxidation, increased nitrite levels and adaptive pathways against oxidative stress in the frontal cortex and striatum. 20592767 2011
Entrez Id: 590
Gene Symbol: BCHE
BCHE 		0.300 Therapeutic disease CTD_human Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine. 20971807 2011
Entrez Id: 5978
Gene Symbol: REST
REST 		0.300 Therapeutic disease CTD_human Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy. 21905079 2011
Entrez Id: 7249
Gene Symbol: TSC2
TSC2 		0.300 Biomarker disease CTD_human Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex. 21062901 2011
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.300 Biomarker disease CTD_human Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus. 21269288 2011
Entrez Id: 54715
Gene Symbol: RBFOX1
RBFOX1 		0.300 Biomarker disease CTD_human The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain. 21623373 2011
Entrez Id: 2247
Gene Symbol: FGF2
FGF2 		0.300 Therapeutic disease CTD_human Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus. 21269288 2011