Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 51741
Gene Symbol: WWOX
WWOX
0.010 GeneticVariation phenotype BEFREE <b>Conclusion:</b> Our findings indicate that WWOX rs9926344 polymorphism is positively correlated with tumor recurrence and can be used as an independent prognostic marker for HCC patients after operation. 29675105 2018
Entrez Id: 84848
Gene Symbol: MIR503HG
MIR503HG
0.010 Biomarker phenotype BEFREE <b>Conclusion:</b> Our findings support a role for miR503HG in tumor recurrence risk and survival prediction in HCC patients. 29774077 2018
Entrez Id: 29126
Gene Symbol: CD274
CD274
0.100 AlteredExpression phenotype BEFREE <b>Conclusion:</b> We found that combination of PD-L1 expression and NLR may be a promising prognostic indicator, and may also be a good marker for tumor recurrence, especially in the patients with wild-type EGFR. 31777599 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 Biomarker phenotype BEFREE <b>Conclusion:</b> We found that combination of PD-L1 expression and NLR may be a promising prognostic indicator, and may also be a good marker for tumor recurrence, especially in the patients with wild-type EGFR. 31777599 2019
Entrez Id: 25859
Gene Symbol: PART1
PART1
0.010 Biomarker phenotype BEFREE <b>Conclusions:</b> PART1 may prove to be a promising biomarker for prediction of survival and tumor recurrence in stage I-III NSCLC. 28819376 2017
Entrez Id: 2324
Gene Symbol: FLT4
FLT4
0.010 Biomarker phenotype BEFREE <b>Results:</b> Patients with VEGFR-3 positive tumors had increased lymph node metastasis (<i>p</i>=0.025) and were more likely to suffer from tumor recurrence compared with VEGFR-3 negative tumors (<i>p</i><0.001). 30123080 2018
Entrez Id: 238
Gene Symbol: ALK
ALK
0.030 GeneticVariation phenotype BEFREE <i>ALK</i> positive patients had a higher risk of developing tumor recurrence in liver (P=0.043). 31737311 2019
Entrez Id: 257000
Gene Symbol: TINCR
TINCR
0.010 Biomarker phenotype BEFREE <i>miR-137</i>/<i>miR-133a</i>-TINCR pathway may serve as a promising target for tumor recurrence and prognosis of patients with HCC. 28546230 2017
Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1
0.030 Biomarker phenotype BEFREE <sup>68</sup>Gallium prostate specific membrane antigen (PSMA) ligand positron emission tomography (PET) is an increasingly used imaging modality in prostate cancer, especially in cases of tumor recurrence after curative intended therapy. 29751842 2018
Entrez Id: 80790
Gene Symbol: CMIP
CMIP
0.010 Biomarker phenotype BEFREE <sup>99m</sup>Tc-MIP-1404 PSMA-SPECT/CT demonstrated a high performance in detecting PSMA-positive lesions suggestive of tumor recurrence in patients with biochemical recurrence of prostate cancer and low and very low serum PSA levels. 31502084 2019
Entrez Id: 354
Gene Symbol: KLK3
KLK3
0.090 AlteredExpression phenotype BEFREE <sup>99m</sup>Tc-MIP-1404 PSMA-SPECT/CT demonstrated a high performance in detecting PSMA-positive lesions suggestive of tumor recurrence in patients with biochemical recurrence of prostate cancer and low and very low serum PSA levels. 31502084 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.100 GeneticVariation phenotype BEFREE (1) Tp53 mutations in the urine sediment could be a useful indicator of tumor recurrence or tumor residual in patients ( approximately 40%) with primary mutated bladder cancer tissue. 11025381 2000
Entrez Id: 79651
Gene Symbol: RHBDF2
RHBDF2
0.010 Biomarker phenotype BEFREE 99mTc-HYNIC-TOC in the Evaluation of Recurrent Tumor-Induced Osteomalacia. 30672760 2019
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
0.030 GeneticVariation phenotype BEFREE Tumor recurrence at 2 years after surgical resection was significantly less common among the hMLH1-methylated PENs (11%), compared with the unmethylated PENs (35%; P=.038). 14668721 2003
Entrez Id: 3815
Gene Symbol: KIT
KIT
0.070 GeneticVariation phenotype BEFREE Tumor recurrence or distant metastasis correlates to both the KIT mutations at codons 557/558 and the mitotic counts, but not to the tumor size. 15742414 2005
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 Biomarker phenotype BEFREE Tumor recurrence in prostate cancer has been attributed to the presence of CD44-expressing tumor-initiating cells. 22552290 2012
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.100 AlteredExpression phenotype BEFREE Tumor recurrence was significantly more frequent in NSCLC patients with survivin and VEGF mRNA positivity postoperation than in patients without (P = 0.003 and P = 0.006, respectively). 23756092 2013
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.100 GeneticVariation phenotype BEFREE Tumor recurrence rates were 25.8% (50 of 194;77.60 recurrences per 1,000 person-years; 95% CI, 58.81 to 102.38) versus 9.6% (30 of 313; 22.88 recurrences per 1,000 person-years; 95% CI, 16.00 to 32.72) in BRAF mutation-positive versus -negative patients (hazard ratio [HR], 3.22; 95% CI, 2.05 to 5.07) and 47.5% (29 of 61; 108.55 recurrences per 1,000 person-years; 95% CI, 75.43 to 156.20) versus 11.4% (51 of 446; 30.21 recurrences per 1,000 person-years; 95% CI, 22.96 to 39.74) in TERT mutation-positive versus -negative patients (HR, 3.46; 95% CI, 2.19 to 5.45). 25024077 2014
Entrez Id: 7015
Gene Symbol: TERT
TERT
0.040 GeneticVariation phenotype BEFREE Tumor recurrence rates were 25.8% (50 of 194;77.60 recurrences per 1,000 person-years; 95% CI, 58.81 to 102.38) versus 9.6% (30 of 313; 22.88 recurrences per 1,000 person-years; 95% CI, 16.00 to 32.72) in BRAF mutation-positive versus -negative patients (hazard ratio [HR], 3.22; 95% CI, 2.05 to 5.07) and 47.5% (29 of 61; 108.55 recurrences per 1,000 person-years; 95% CI, 75.43 to 156.20) versus 11.4% (51 of 446; 30.21 recurrences per 1,000 person-years; 95% CI, 22.96 to 39.74) in TERT mutation-positive versus -negative patients (HR, 3.46; 95% CI, 2.19 to 5.45). 25024077 2014
Entrez Id: 84864
Gene Symbol: RIOX2
RIOX2
0.010 Biomarker phenotype BEFREE Tumor recurrence was significantly higher in the Mina53‑positive group than in the Mina53‑negative group. 29750310 2018
Entrez Id: 174
Gene Symbol: AFP
AFP
0.100 AlteredExpression phenotype BEFREE Recurrent tumor in patients with HCC occurred in four cases after surgery (range, 6-15 months) and did not correlate with AFP mRNA positivity before surgery, during surgery, or after surgery. 9242336 1997
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.060 Biomarker phenotype BEFREE MMP-2 and its ratio to TIMP-2 have been associated with tumor recurrence and progression in a number of human malignancies. 10579795 2000
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
0.010 Biomarker phenotype BEFREE PCNA labeling index correlated less impressively with tumor recurrence (mean = 28.59% for treatment failures, mean = 21.75% for nonfailures, P = .022). 10852523 2000
Entrez Id: 1485
Gene Symbol: CTAG1B
CTAG1B
0.010 AlteredExpression phenotype BEFREE NY-ESO-1 expression in primary MTC tissues significantly correlated with tumor recurrence. 12574209 2003
Entrez Id: 246100
Gene Symbol: CTAG1A
CTAG1A
0.010 AlteredExpression phenotype BEFREE NY-ESO-1 expression in primary MTC tissues significantly correlated with tumor recurrence. 12574209 2003