Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 Biomarker disease BEFREE Adiponectin and metabolic syndrome. 14551151 2004
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 Biomarker disease BEFREE Adiponectin gene SNPs may have several phenotypic effects that co-occur with the development of the metabolic syndrome. 15047634 2004
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 Biomarker disease BEFREE Adiponectin is one of the key molecules in the metabolic syndrome, and its concentration is decreased in obesity, type-2 diabetes, and coronary artery disease. 15123570 2004
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 GeneticVariation disease BEFREE Adiponectin and its gene variants as risk factors for insulin resistance, the metabolic syndrome and cardiovascular disease. 16581078 2006
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 AlteredExpression disease BEFREE Adiponectin, a protein exclusively secreted by adipose tissue but present at low levels in obesity, is now widely recognised as a key determinant of insulin sensitivity and of protection against obesity-associated metabolic syndrome. 17112391 2006
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 Biomarker disease BEFREE Adiponectin SNP276 is associated with obesity, the metabolic syndrome, and diabetes in the elderly. 17684226 2007
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 Biomarker disease BEFREE Adiponectin is an adipose tissue-specific plasma protein that inversely associates with metabolic syndrome. 18160463 2008
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 Biomarker disease CTD_human Adiponectin as a potential biomarker for the metabolic syndrome in Chinese patients taking clozapine for schizophrenia. 18162013 2007
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 Biomarker disease BEFREE Adiponectin is widely known as an adipocytokine with therapeutic potential for its markedly protective function in the pathogenesis of obesity-related disorders, metabolic syndrome, systemic insulin resistance, cardiovascular disease and more recently carcinogenesis. 19483724 2009
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 Biomarker disease BEFREE Adiponectin (Ad) is reported to reduce insulin resistance in metabolic syndrome. 19533865 2008
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 GeneticVariation disease BEFREE Adiponectin gene polymorphisms were associated with obesity and metabolic syndrome parameters in Tunisian volunteers. 21870907 2011
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 AlteredExpression disease BEFREE Adiponectin level and gene variability are obesity and metabolic syndrome markers in a young population. 22374249 2012
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 AlteredExpression disease BEFREE Adiponectin, a protein exclusively secreted by adipose tissue and present at low levels in obese individuals, is now widely recognized as a key determinant of insulin sensitivity and protection against obesity-associated metabolic syndrome. 23041553 2013
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 Biomarker disease BEFREE Adiponectin is a key molecule involved in metabolic syndrome. 23047599 2013
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 GeneticVariation disease BEFREE Adiponectin gene polymorphisms SNP45 and SNP276 have been related to metabolic syndrome (MS) and related pathologies, including obesity. 23108996 2013
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 AlteredExpression disease BEFREE Adiponectin levels were found to be highly intercorrelated phenotypically with the majority of MetS traits. 23628382 2013
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 Biomarker disease BEFREE Adiponectin, a secretagogue exclusively produced by adipocytes, has been associated with metabolic features, but its role in the development of the metabolic syndrome remains unclear. 23826141 2013
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 Biomarker disease BEFREE Adiponectin Q is a hormone that modulates several metabolic processes and contributes to the suppression of biochemical pathways leading to metabolic syndrome. 24330659 2013
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 Biomarker disease BEFREE Adiponectin secreted from adipose tissue is assumed to mediate protective effects on development of metabolic syndrome (MetS) and MetS-related diseases such as cardiovascular diseases and cancer. 24749767 2014
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 GeneticVariation disease BEFREE ADIPOQ rs266729 G/C gene polymorphism and plasmatic adipocytokines connect metabolic syndrome to colorectal cancer. 28529612 2017
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 Biomarker disease BEFREE Adiponectin regulates glucose and lipid metabolism, acting against atherosclerosis and metabolic syndrome. 28606559 2017
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 AlteredExpression disease BEFREE Adiponectin levels were lower in Obese compared to Control, but lowest in MetS (p<0.05). 28638270 2017
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 Biomarker disease BEFREE Adiponectin was inversely associated with MetS and high AS (both <i>P</i> < 0.001). 28670347 2017
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 Biomarker disease BEFREE Adiponectin, leptin and hs-CRP were significantly modified in the group with MetS (p=0.04, p=0.04, p=0.01, respectively). 30530892 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.400 Biomarker disease BEFREE Adiponectin, an adipokine secreted by adipocytes, exerts favorable effects in the milieu of diabetes and metabolic syndrome through its anti-inflammatory, antifibrotic, and antioxidant effects. 30974901 2019