Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3636
Gene Symbol: INPPL1
INPPL1
0.350 GeneticVariation disease BEFREE These results suggest that INPPL1 variants may be involved in mechanisms causing hypertension in metabolic syndrome patients specifically. 17557929 2007
Entrez Id: 3636
Gene Symbol: INPPL1
INPPL1
0.350 AlteredExpression disease BEFREE SHIP2 mouse models and genetic studies in human propose that increased expression or activity of SHIP2 contributes to the pathogenesis of the metabolic syndrome, hypertension and type 2 diabetes. 31342643 2020
Entrez Id: 3636
Gene Symbol: INPPL1
INPPL1
0.350 GeneticVariation disease BEFREE We conclude that INPPL1 variants may impact susceptibility to disease and/or to subphenotypes involved in the metabolic syndrome in some diabetic patients. 15220217 2004
Entrez Id: 3636
Gene Symbol: INPPL1
INPPL1
0.350 Biomarker disease BEFREE The aim of this study was to investigate if the INPPL1 (inositol polyphosphate phosphatase-like 1) gene encoding lipid phosphatase SHIP2 is associated with the metabolic syndrome and diabetic nephropathy in Finnish people with Type 1 diabetes. 22486725 2012
Entrez Id: 3636
Gene Symbol: INPPL1
INPPL1
0.350 GeneticVariation disease BEFREE Because some single-nucleotide polymorphisms (SNP) of the gene encoding SHIP2 were significantly associated in T2DM patients with metabolic syndrome and some related conditions, we decided to conduct a case-control study on this gene, analyzing AD and T2DM subjects as cases and young, old, and centenarians as controls. 24313349 2014
Entrez Id: 3636
Gene Symbol: INPPL1
INPPL1
0.350 Biomarker disease CTD_human We conclude that INPPL1 variants may impact susceptibility to disease and/or to subphenotypes involved in the metabolic syndrome in some diabetic patients. 15220217 2004