Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
0.100 Biomarker disease BEFREE The aim of this study was to perform a systematic review and meta-analysis of randomized controlled trials (RCTs) and observational studies to assess the association between VD and MetS or its components (systolic blood pressure [SBP], diastolic blood pressure [DBP], fasting glucose triglycerides, waist circumference [WC], HDL-cholesterol (HDL-C)) in adults. 29907356 2019
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
0.100 GeneticVariation disease BEFREE MS: Metabolic syndrome; WC: Waist circumference; TG: Triglycerides; HDL-c: High-density lipoprotein cholesterol; BP: Blood pressure; SBP: Systolic blood pressure, DBP: Diastolic blood pressure; PA: Physical activity; JIS: Joint Interim Statement; CVD: Cardiovascular disease; ATP III: US Third Report of the National Cholesterol Education Program, the Adult Treatment Panel; IDF: International Diabetes Federation; IPAQ: International Physical Activity Questionnaire; BMI: Body mass index; CDC: the Nantong Centers for Disease Control; OR: Odds ratio; CI: Confidence interval; SD: Standard deviation; IQR: Interquartile range. 29345215 2018
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
0.100 Biomarker disease BEFREE AGHD = adult growth hormone deficiency; ASCVD = atherosclerotic cardiovascular disease; AUROC = area under the receiver operating characteristic curve; BMI = body mass index; CVAI = Chinese visceral adiposity index; CVD = cardiovascular disease; DBP = diastolic blood pressure; GH = growth hormone; GHRT = GH replacement therapy; HDL-C = high-density lipoprotein cholesterol; IGF-1 = insulin like factor-1; IGFBP-3 = insulin like factor binding protein-3; IR = insulin resistance; LAP = lipid accumulation product; MS = metabolic syndrome; SBP = systolic blood pressure; TC = total cholesterol; TG = triglycerides; VAI = visceral adiposity index; WC = waist circumference; WHR = waist-to-hip ratio. 29144802 2018
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
0.100 Biomarker disease BEFREE Baseline characteristics were similar in the two SBP target groups within each MetS subgroup, except body mass index was slightly higher in the standard arm of the MetS subgroup (33.3 ± 5.6 vs 33.0 ± 5.3 kg/m<sup>2</sup> ; P < .01), but were similar across treatment arms in the non-MetS subgroup. 29024310 2018
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
0.100 Biomarker disease BEFREE This relationship was also observed in MetS components (BMI and SBP). 30157802 2018
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
0.100 Biomarker disease BEFREE J Strength Cond Res XX(X): 000-000, 2018-The purpose of this study was to identify and summarize the relationships between muscular fitness (MF) and individual components of metabolic syndrome (high waist circumference [WC], high blood pressure [BP], high systolic BP [SBP], high diastolic BP [DBP], high triglycerides [TG], fasting blood glucose [FG], and low HDL cholesterol levels [HDL-C]) in children and adolescents. 30273286 2018
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
0.100 Biomarker disease BEFREE Simple logistic analysis showed that sex (OR 3.50, 95% CI 1.21-10.12, p = 0.021), age (OR 1.14, 95% CI 1.07-1.21, p<0.001), BMI (OR 1.11, 95% CI 1.01-1.22, p = 0.028), waist circumference (OR 1.06, 95% CI 1.02-1.10, p = 0.002), SBP (OR 1.03, 95% CI 1.01-1.04, p = 0.003), DBP (OR 1.03, 95% CI 1.00-1.06, p = 0.030), HDL-C (OR 0.97, 95% CI 0.94-1.00, p = 0.026), uric acid (OR 1.84, 95% CI 1.49-2.27, p<0.001), metabolic syndrome (OR 2.68, 95% CI 1.29-5.67, p = 0.009), and decreased BMD (OR 3.998, 95% CI 1.38-11.57, p = 0.011) were significantly associated with CKD. 29320555 2018
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
0.100 GeneticVariation disease BEFREE Eight of them were normotensive and eleven hypertensive according to MetS threshold (≥130 mmHg for SBP and/or ≥85 mmHg for DBP). 28493030 2017
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
0.100 Biomarker disease BEFREE Besides, sex, age, WC, SBP, DBP, ALT, FG, UAC, TG, HDL-C and LDL-C are risk factors for MetS after multivariate adjustment. 28740055 2017
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
0.100 AlteredExpression disease BEFREE AChE activity was associated with BP status and SBP, whereas BChE activity was associated with features of the metabolic syndrome (especially body weight and BMI). 21493754 2011