Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 AlteredExpression disease BEFREE Metabolic syndrome is associated with the accumulation of CER in VAT, possibly related to increased FAT/CD36 protein expression. 30724038 2019
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 Biomarker disease BEFREE In this study, we tested our hypothesis that the periodontal expression of fatty acid receptors GPR40 and CD36 is increased in patients with both MetS and periodontitis. 30597558 2019
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 GeneticVariation disease BEFREE The FA receptor CD36 has been linked to risk of metabolic syndrome. 29546316 2018
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 Biomarker disease BEFREE In the past decade, microvesicles (MVs) and CD36 have increasingly been considered as possible biomarkers for obesity, the metabolic syndrome (MetSy), type 2 diabetes mellitus (T2DM). 30386406 2018
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 Biomarker disease BEFREE Cluster of differentiation 36 (CD36), also named fatty acid translocase, is known to facilitate long-chain fatty acid uptake and contribute to the development of MS. We recently found that CD36 overexpression enhanced HBV replication. 28697919 2017
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 Biomarker disease BEFREE <i>Conclusions.</i> Metabolic syndrome components and hepatic fat accumulation correlated with microvesicle phenotypes, supporting the involvement of especially CD36 on monocytes in metabolic syndrome pathogenesis. 28168203 2017
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 AlteredExpression disease BEFREE CD36 expression is upregulated in mice with periodontitis and MetS and involved in gene expression in macrophages stimulated by palmitate and LPS. 27753178 2017
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 GeneticVariation disease BEFREE Effect of chronic sildenafil treatment on IS and FMD was tested in AA women with metabolic syndrome and with/without the CD36 variant, using a randomized, placebo-controlled trial (protocol 2). 27144937 2016
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 GeneticVariation disease BEFREE Remarkably, rs11760281 in GNAT3 and rs1194197 near CD36 exhibited the strongest associations with MS (P = 0.0003, relative risk (RR) = 1.6 and P = 0.004, RR = 1.7, respectively) and several other related traits. 22456541 2012
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 Biomarker disease BEFREE CD36 is recognized as a lipid and fatty acid receptor and plays an important role in the metabolic syndrome and associated cardiac events. 22662181 2012
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 GeneticVariation disease BEFREE Overall, the haplotype tagged SNPs of CD36 gene were not related to the risk of metabolic syndrome. 23249574 2012
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 GeneticVariation disease BEFREE Genetic variants of the CD36 gene have been associated with metabolic syndrome (MetS). 22047506 2012
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 GeneticVariation disease BEFREE Our findings show that CD36 rs1761667 SNP is positively associated with increased risk of MetS and its components with genotype AG heterozygotes showing highest frequency among MetS patients. 22588808 2012
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 Biomarker disease BEFREE In this review we will describe the functions of CD36 in tissues and address the role of sCD36 in the context of the metabolic syndrome. 21250778 2011
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 GeneticVariation disease BEFREE In humans, CD36 variants have been identified to influence free FA and high-density lipoprotein (HDL) levels and to associate with the risk of the metabolic syndrome, coronary artery disease and stroke. 20935172 2011
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 GeneticVariation disease BEFREE SNPs of CD36 were associated with metabolic syndrome in Puerto Ricans. 20223461 2010
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 GeneticVariation disease BEFREE In addition, variants in the CD36 gene were shown recently to influence susceptibility for the metabolic syndrome, which greatly increases the risk of diabetes and heart disease. 19185504 2009
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 Biomarker disease BEFREE We evaluated 36 tag SNPs across CD36 in the HyperGen population sample of 2020 African-Americans for impact on the MetS and its quantitative traits. 18305138 2008
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 Biomarker disease BEFREE Such studies have also indicated that naturally occurring variation in genes, such as Cd36, that regulate fatty acid metabolism and ectopic accumulation of fat and fat metabolites can influence both biochemical and hemodynamic features of the metabolic syndrome and mediate the antidiabetic effects of drugs that activate the peroxisome proliferator-activated receptor-gamma. 17339535 2007
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 Biomarker disease BEFREE The membrane-bound fatty acid transporter CD36/FAT may play a role in disturbed fatty acid handling as observed in the metabolic syndrome and Type 2 diabetes mellitus (T2DM). 16911630 2006
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 Biomarker disease BEFREE In conclusion, we have revealed that defective Cd36 is probably a candidate gene for disorded fatty-acid metabolism, glucose intolerance and insulin resistance in NIH-derived SHR, but other genes might play a role in pathogenesis of metabolic syndrome in Prague hereditary hypertriglyceridemic rats. 15209533 2004
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 Biomarker disease BEFREE Genetics of Cd36 and the hypertension metabolic syndrome. 11891508 2002
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 GeneticVariation disease BEFREE Association of the Pro90Ser CD36 mutation with elevated free fatty acid concentrations but not with insulin resistance syndrome in Japanese. 11718687 2001
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 Biomarker disease RGD Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats. 9916795 1999