Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.050 GeneticVariation disease BEFREE The distribution of TCR beta alleles showed ethnic variation, with one allele significantly decreased in Australian Aborigines, but there was no association with chronic hepatitis B. 1349565 1992
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.100 Biomarker disease BEFREE These data suggest that interferon gamma does not have a powerful antiviral effect on chronic hepatitis B in children.However, it is well tolerated. 1641292 1992
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.400 Biomarker disease BEFREE In this study, binding characteristics of interferon-alpha to peripheral blood mononuclear cells in patients with chronic hepatitis B virus infection were studied using radioiodinated recombinant interferon-alpha 2b to determine interferon-alpha receptor numbers and dissociation constants. 1825307 1991
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.400 Biomarker disease BEFREE In a randomized controlled trial of recombinant alpha-2a interferon for chronic hepatitis B, interferon antibodies developed in 21 (39%) of 54 Chinese adults who received IFN. 2258142 1990
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13
0.100 Biomarker disease BEFREE In a randomized controlled trial of recombinant alpha-2a interferon for chronic hepatitis B, interferon antibodies developed in 21 (39%) of 54 Chinese adults who received IFN. 2258142 1990
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
0.100 Biomarker disease BEFREE In a randomized controlled trial of recombinant alpha-2a interferon for chronic hepatitis B, interferon antibodies developed in 21 (39%) of 54 Chinese adults who received IFN. 2258142 1990
Entrez Id: 3493
Gene Symbol: IGHA1
IGHA1
0.010 Biomarker disease BEFREE Thus, in contrast to HBcAg, HBeAg does not trigger a persistent IgM and IgA1 response in chronic hepatitis B. 2303802 1990
Entrez Id: 353
Gene Symbol: APRT
APRT
0.020 AlteredExpression disease BEFREE Differential effect of ARA-AMP on serum DNA polymerase activity and serum HBV-DNA in chronic hepatitis B virus infection. A possible reason for lack of efficacy. 2439580 1986
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
0.020 AlteredExpression disease BEFREE Differential effect of ARA-AMP on serum DNA polymerase activity and serum HBV-DNA in chronic hepatitis B virus infection. A possible reason for lack of efficacy. 2439580 1986
Entrez Id: 368
Gene Symbol: ABCC6
ABCC6
0.010 AlteredExpression disease BEFREE Differential effect of ARA-AMP on serum DNA polymerase activity and serum HBV-DNA in chronic hepatitis B virus infection. A possible reason for lack of efficacy. 2439580 1986
Entrez Id: 5063
Gene Symbol: PAK3
PAK3
0.010 AlteredExpression disease BEFREE Differential effect of ARA-AMP on serum DNA polymerase activity and serum HBV-DNA in chronic hepatitis B virus infection. A possible reason for lack of efficacy. 2439580 1986
Entrez Id: 2296
Gene Symbol: FOXC1
FOXC1
0.010 AlteredExpression disease BEFREE Differential effect of ARA-AMP on serum DNA polymerase activity and serum HBV-DNA in chronic hepatitis B virus infection. A possible reason for lack of efficacy. 2439580 1986
Entrez Id: 4264
Gene Symbol: MHS2
MHS2
0.010 GeneticVariation disease BEFREE Mutations in MHS1 (codon 21-34), but not in MHS2 (codon 85-100), are more likely to be related to the severity of CH-B. 7495779 1995
Entrez Id: 6261
Gene Symbol: RYR1
RYR1
0.010 Biomarker disease BEFREE A longitudinal study using sequential samples is warranted to further clarify the role of MHS1 in the pathogenesis of more severe CH-B. 7495779 1995
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.050 Biomarker disease BEFREE The influence of a maternal chronic hepatitis B virus infection on the repertoire of transcribed T-cell receptor beta chain variable region genes in human cord blood. 7557848 1995
Entrez Id: 213
Gene Symbol: ALB
ALB
0.060 Biomarker disease BEFREE Compared with a similar ara-AMP complex with lactosaminated human albumin, currently being studied in clinical trials for the treatment of chronic type B hepatitis, which must be infused intravenously, the present conjugate might provide more patient compliance because of IM administration. 7557853 1995
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
0.020 Biomarker disease BEFREE Compared with a similar ara-AMP complex with lactosaminated human albumin, currently being studied in clinical trials for the treatment of chronic type B hepatitis, which must be infused intravenously, the present conjugate might provide more patient compliance because of IM administration. 7557853 1995
Entrez Id: 353
Gene Symbol: APRT
APRT
0.020 Biomarker disease BEFREE Compared with a similar ara-AMP complex with lactosaminated human albumin, currently being studied in clinical trials for the treatment of chronic type B hepatitis, which must be infused intravenously, the present conjugate might provide more patient compliance because of IM administration. 7557853 1995
Entrez Id: 2875
Gene Symbol: GPT
GPT
0.100 Biomarker disease BEFREE In patients with chronic hepatitis B and in anti-HBe-positive asymptomatic carriers, increased prevalence of the preC mutant was associated with the development of anti-HBe antibodies and normalization of the serum alanine aminotransferase concentration. 7595419 1995
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.100 AlteredExpression disease BEFREE The expression of IL-2, IL-4 and interferon-gamma (IFN-gamma) mRNA using liver biopsies at different phases of acute exacerbation of chronic hepatitis B. 7774054 1995
Entrez Id: 3558
Gene Symbol: IL2
IL2
0.050 AlteredExpression disease BEFREE The expression of IL-2, IL-4 and interferon-gamma (IFN-gamma) mRNA using liver biopsies at different phases of acute exacerbation of chronic hepatitis B. 7774054 1995
Entrez Id: 3565
Gene Symbol: IL4
IL4
0.040 AlteredExpression disease BEFREE The expression of IL-2, IL-4 and interferon-gamma (IFN-gamma) mRNA using liver biopsies at different phases of acute exacerbation of chronic hepatitis B. 7774054 1995
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.400 Biomarker disease BEFREE Recombinant interferon-alpha 2a hastens the rate of HBeAg clearance in children with chronic hepatitis B. 8045488 1994
Entrez Id: 3558
Gene Symbol: IL2
IL2
0.050 Biomarker disease BEFREE Pilot study of natural human interleukin-2 in patients with chronic hepatitis B. Immunomodulatory and antiviral effects. 8301059 1993
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1
0.020 Biomarker disease BEFREE Pilot study of ribavirin and interferon-beta for chronic hepatitis B. 8340055 1993