|
HLA-DPB1
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Association between chronic hepatitis B virus infection and HLA-DP gene polymorphisms in the Turkish population.
|
28119119 |
2017 |
|
HLA-DPB1
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Single nucleotide polymorphisms (SNPs) in HLA-DP (rs9277535 and rs3077) and HLA-DQ (rs2856718 and rs7453920) have been repeatedly associated with chronic hepatitis B and spontaneous HBV clearance.
|
28882445 |
2017 |
|
HLA-DPB1
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
This study aimed to investigate the association of two single nucleotide polymorphism (SNPs), one in the HLA-DPB1 (rs9277535) and one in the HLA-DQB2 (rs7453920), with chronic hepatitis B infection in a southern Brazilian sample.
|
28613373 |
2017 |
|
HLA-DPB1
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B.
|
25802187 |
2015 |
|
HLA-DPB1
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Effects of HLA-DPB1 genotypes on chronic hepatitis B infection in Japanese individuals.
|
26449183 |
2015 |
|
HLA-DPB1
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
To investigate the association of HLA-DP polymorphisms with response to peginterferon (PEG-IFN) in Caucasian chronic hepatitis B (CHB) patients.
|
25109699 |
2014 |
|
HLA-DPB1
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese.
|
24940741 |
2014 |
|
HLA-DPB1
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Previous studies showed that single nucleotide polymorphisms (SNPs) in the HLA-DP, TCF19 and EHMT2 genes may affect the chronic hepatitis B (CHB).
|
24465836 |
2014 |
|
HLA-DPB1
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Some variants of the HLA-DP locus (HLA-DPA1 A allele and HLA-DPB1) protect against progression of chronic hepatitis B infection.
|
24654629 |
2014 |
|
HLA-DPB1
|
0.500 |
AlteredExpression
|
disease |
BEFREE |
HLA-DP and γ-interferon receptor-2 gene variants and their association with viral hepatitis activity in chronic hepatitis B infection.
|
23980639 |
2014 |
|
HLA-DPB1
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
However, whether there exists an association between HLA-DP variants and the progression of CHBVI remains to be determined.
|
24846544 |
2014 |
|
HLA-DPB1
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
HLA-DP and IL28B polymorphisms: influence of host genome on hepatitis B surface antigen seroclearance in chronic hepatitis B.
|
23449268 |
2013 |
|
HLA-DPB1
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
We also found that the HLA-DPA1 and HLA-DPB1 genes were significantly associated with protective effects against chronic hepatitis B (CHB) in Japanese, Korean and other Asian populations, including Chinese and Thai individuals (P(meta) = 4.40×10⁻¹⁹ for rs3077 and P(meta) = 1.28×10⁻¹⁵ for rs9277542).
|
22737229 |
2012 |
|
HLA-DPB1
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Relationship between HLA-DP gene polymorphisms and clearance of chronic hepatitis B virus infections: case-control study and meta-analysis.
|
22543033 |
2012 |
|
HLA-DPB1
|
0.500 |
AlteredExpression
|
disease |
BEFREE |
Risk alleles for chronic hepatitis B are associated with decreased mRNA expression of HLA-DPA1 and HLA-DPB1 in normal human liver.
|
21346778 |
2011 |
|
HLA-DPB1
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
To identify host genetic factors that are associated with chronic hepatitis B (CHB) susceptibility, we previously conducted a two-stage genome-wide association study (GWAS) and identified the association of HLA-DP variants with CHB in Asians; however, only 179 cases and 934 controls were genotyped using genome-wide single nucleotide polymorphism (SNP) arrays.
|
21750111 |
2011 |
|
HLA-DPB1
|
0.500 |
Biomarker
|
disease |
CTD_human |
Through a two-stage genome-wide association study using 786 Japanese chronic hepatitis B cases and 2,201 controls, we identified a significant association of chronic hepatitis B with 11 SNPs in a region including HLA-DPA1 and HLA-DPB1.
|
19349983 |
2009 |
|
HLA-DPB1
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Through a two-stage genome-wide association study using 786 Japanese chronic hepatitis B cases and 2,201 controls, we identified a significant association of chronic hepatitis B with 11 SNPs in a region including HLA-DPA1 and HLA-DPB1.
|
19349983 |
2009 |
|
HLA-DPA1
|
0.440 |
GeneticVariation
|
disease |
GWASCAT |
Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B.
|
25802187 |
2015 |
|
HLA-DPA1
|
0.440 |
GeneticVariation
|
disease |
BEFREE |
Some variants of the HLA-DP locus (HLA-DPA1 A allele and HLA-DPB1) protect against progression of chronic hepatitis B infection.
|
24654629 |
2014 |
|
HLA-DPA1
|
0.440 |
GeneticVariation
|
disease |
GWASCAT |
A genome-wide association study identified new variants associated with the risk of chronic hepatitis B.
|
23760081 |
2013 |
|
HLA-DPA1
|
0.440 |
GeneticVariation
|
disease |
BEFREE |
We also found that the HLA-DPA1 and HLA-DPB1 genes were significantly associated with protective effects against chronic hepatitis B (CHB) in Japanese, Korean and other Asian populations, including Chinese and Thai individuals (P(meta) = 4.40×10⁻¹⁹ for rs3077 and P(meta) = 1.28×10⁻¹⁵ for rs9277542).
|
22737229 |
2012 |
|
HLA-DPA1
|
0.440 |
AlteredExpression
|
disease |
BEFREE |
Risk alleles for chronic hepatitis B are associated with decreased mRNA expression of HLA-DPA1 and HLA-DPB1 in normal human liver.
|
21346778 |
2011 |
|
HLA-DPA1
|
0.440 |
Biomarker
|
disease |
CTD_human |
Through a two-stage genome-wide association study using 786 Japanese chronic hepatitis B cases and 2,201 controls, we identified a significant association of chronic hepatitis B with 11 SNPs in a region including HLA-DPA1 and HLA-DPB1.
|
19349983 |
2009 |
|
HLA-DPA1
|
0.440 |
GeneticVariation
|
disease |
BEFREE |
Through a two-stage genome-wide association study using 786 Japanese chronic hepatitis B cases and 2,201 controls, we identified a significant association of chronic hepatitis B with 11 SNPs in a region including HLA-DPA1 and HLA-DPB1.
|
19349983 |
2009 |