Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 Biomarker disease CTD_human Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. 19734902 2009
Entrez Id: 498
Gene Symbol: ATP5F1A
ATP5F1A
0.300 Biomarker disease CTD_human Proteomic identification of HNE-bound proteins in early Alzheimer disease: Insights into the role of lipid peroxidation in the progression of AD. 19374891 2009
Entrez Id: 945
Gene Symbol: CD33
CD33
0.300 Biomarker disease CTD_human Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. 21460840 2011
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.300 Biomarker disease CTD_human Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. 17192785 2007
Entrez Id: 5336
Gene Symbol: PLCG2
PLCG2
0.300 Biomarker disease CTD_human Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. 28714976 2017
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.300 Biomarker disease CTD_human Alzheimer disease risk and genetic variation in ACE: a meta-analysis. 14872014 2004
Entrez Id: 406938
Gene Symbol: MIR146A
MIR146A
0.300 Biomarker disease CTD_human Up-regulation of NF-kB-sensitive miRNA-125b and miRNA-146a in metal sulfate-stressed human astroglial (HAG) primary cell cultures. 22099153 2011
Entrez Id: 3482
Gene Symbol: IGF2R
IGF2R
0.300 Biomarker disease CTD_human Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes? 15750215 2005
Entrez Id: 55676
Gene Symbol: SLC30A6
SLC30A6
0.300 Biomarker disease CTD_human Altered expression of zinc transporters-4 and -6 in mild cognitive impairment, early and late Alzheimer's disease brain. 16580781 2006
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.300 Biomarker disease CTD_human Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease. 18077176 2008
Entrez Id: 4129
Gene Symbol: MAOB
MAOB
0.300 Biomarker disease CTD_human Up-regulation of the isoenzymes MAO-A and MAO-B in the human basal ganglia and pons in Huntington's disease revealed by quantitative enzyme radioautography. 21075085 2011
Entrez Id: 3643
Gene Symbol: INSR
INSR
0.300 Biomarker disease CTD_human Long-term oral galactose treatment prevents cognitive deficits in male Wistar rats treated intracerebroventricularly with streptozotocin. 24055495 2014
Entrez Id: 1378
Gene Symbol: CR1
CR1
0.300 Biomarker disease CTD_human Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. 19734903 2009
Entrez Id: 351
Gene Symbol: APP
APP
0.300 Biomarker disease CTD_human APP/PS1 transgenic mice treated with aluminum: an update of Alzheimer's disease model. 22507317 2012
Entrez Id: 1191
Gene Symbol: CLU
CLU
0.300 Biomarker disease CTD_human Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. 21460841 2011
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1
0.300 Biomarker disease CTD_human APP/PS1 transgenic mice treated with aluminum: an update of Alzheimer's disease model. 22507317 2012
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
0.300 Biomarker disease CTD_human Lithium treatment induces proteasomal degradation of over-expressed acetylcholinesterase (AChE-S) and inhibit GSK3β. 22944069 2013
Entrez Id: 23621
Gene Symbol: BACE1
BACE1
0.300 Biomarker disease CTD_human Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma. 16407166 2006
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1
0.300 Biomarker disease CTD_human Beta-amyloid mediated nitration of manganese superoxide dismutase: implication for oxidative stress in a APPNLH/NLH X PS-1P264L/P264L double knock-in mouse model of Alzheimer's disease. 16651627 2006
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 Biomarker disease CTD_human Testosterone modifies the effect of APOE genotype on hippocampal volume in middle-aged men. 20819998 2010
Entrez Id: 406892
Gene Symbol: MIR100
MIR100
0.300 Biomarker disease CTD_human MicroRNA Profiling of CSF Reveals Potential Biomarkers to Detect Alzheimer`s Disease. 25992776 2015
Entrez Id: 351
Gene Symbol: APP
APP
0.300 Biomarker disease CTD_human Impaired modulation of GABAergic transmission by muscarinic receptors in a mouse transgenic model of Alzheimer's disease. 12746438 2003
Entrez Id: 406938
Gene Symbol: MIR146A
MIR146A
0.300 Biomarker disease CTD_human MicroRNA Profiling of CSF Reveals Potential Biomarkers to Detect Alzheimer`s Disease. 25992776 2015
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1
0.300 Biomarker disease CTD_human Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. 7596406 1995
Entrez Id: 7019
Gene Symbol: TFAM
TFAM
0.300 Biomarker disease CTD_human Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. 17192785 2007