×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.700
CausalMutation
disease
CLINVAR
×
Entrez Id:
51741
Gene Symbol:
WWOX
WWOX
0.610
CausalMutation
disease
CLINVAR
×
Entrez Id:
51741
Gene Symbol:
WWOX
WWOX
0.610
Biomarker
disease
CTD_human
×
Entrez Id:
51741
Gene Symbol:
WWOX
WWOX
0.610
CausalMutation
disease
CGI
×
Entrez Id:
7048
Gene Symbol:
TGFBR2
TGFBR2
0.600
CausalMutation
disease
CLINVAR
×
Entrez Id:
7048
Gene Symbol:
TGFBR2
TGFBR2
0.600
CausalMutation
disease
CGI
×
Entrez Id:
1956
Gene Symbol:
EGFR
EGFR
0.600
CausalMutation
disease
CGI
×
Entrez Id:
6049
Gene Symbol:
RNF6
RNF6
0.500
Biomarker
disease
CTD_human
×
Entrez Id:
6049
Gene Symbol:
RNF6
RNF6
0.500
CausalMutation
disease
CGI
×
Entrez Id:
1630
Gene Symbol:
DCC
DCC
0.500
Biomarker
disease
CTD_human
×
Entrez Id:
1630
Gene Symbol:
DCC
DCC
0.500
CausalMutation
disease
CGI
×
Entrez Id:
11178
Gene Symbol:
LZTS1
LZTS1
0.500
Biomarker
disease
CTD_human
×
Entrez Id:
11178
Gene Symbol:
LZTS1
LZTS1
0.500
CausalMutation
disease
CGI
×
Entrez Id:
26272
Gene Symbol:
FBXO4
FBXO4
0.300
GeneticVariation
disease
UNIPROT
×
Entrez Id:
1956
Gene Symbol:
EGFR
EGFR
0.600
GeneticVariation
disease
BEFREE
Our results suggest that enhanced transcription of the epidermal growth factor receptor gene is associated with the development of some esophageal cancers .
3044581
1988
×
Entrez Id:
1956
Gene Symbol:
EGFR
EGFR
0.600
AlteredExpression
disease
BEFREE
Thus, changes in gene copy number or level of expression of HER-I or c-myc DNA sequences may play an important role in the pathogenesis of esophageal cancer in this high-risk region.
2459070
1988
×
Entrez Id:
1950
Gene Symbol:
EGF
EGF
0.080
Biomarker
disease
BEFREE
Amplification of the EGF receptor and c-myc genes in human esophageal cancers .
2459070
1988
×
Entrez Id:
4609
Gene Symbol:
MYC
MYC
0.060
Biomarker
disease
BEFREE
Amplification of the EGF receptor and c-myc genes in human esophageal cancers .
2459070
1988
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.700
GeneticVariation
disease
BEFREE
Frequent mutation of the p53 gene in human esophageal cancer .
2263646
1990
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.700
Biomarker
disease
BEFREE
However, the finding of p53 mutations in Barrett's epithelium adjacent to adenocarcinomas may have clinical implications for p53 as a premalignant marker for esophageal cancer .
1943188
1991
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.700
GeneticVariation
disease
BEFREE
Archival analysis of p53 genetic and protein alterations in Chinese esophageal cancer .
1923503
1991
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.700
PosttranslationalModification
disease
BEFREE
The identification of allelic loss in approximately half of the tumors analyzed supports the hypothesis that inactivation of p53 is involved in the pathogenesis of esophageal cancer .
2052580
1991
×
Entrez Id:
27306
Gene Symbol:
HPGDS
HPGDS
0.070
AlteredExpression
disease
BEFREE
Expression of glutathione S-transferase -pi messenger RNA in human esophageal cancers .
2015556
1991
×
Entrez Id:
133482
Gene Symbol:
SLCO6A1
SLCO6A1
0.040
Biomarker
disease
BEFREE
The results obtained from the current experiment thus suggests that GST -pi might be a useful marker for human esophageal cancer .
2015556
1991
×
Entrez Id:
373156
Gene Symbol:
GSTK1
GSTK1
0.040
Biomarker
disease
BEFREE
The results obtained from the current experiment thus suggests that GST -pi might be a useful marker for human esophageal cancer .
2015556
1991