Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.040 Biomarker disease BEFREE Increased TLR4 in human esophageal cancer has been correlated with its carcinogenesis. 30292843 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.040 AlteredExpression disease BEFREE Mechanically, CEH activated TLR4 and MYD88 innate immune signaling, which is advantageous for the activation of the host's innate immunity to exert a balanced intestinal environment as well as to trigger a better chemotherapeutic response to esophageal cancer. 31293986 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.040 Biomarker disease BEFREE We also suggested that MAPK activation was regulated by the TLR4 pathway and that blocking the TLR4 and MAPK pathways significantly suppressed proliferation and induced apoptosis of esophageal cancer cells. 27323819 2016
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.040 GeneticVariation disease BEFREE Genes identified included those previously associated with esophageal cancer and, interestingly, a group of genes encoding proteins involved in the regulation of the TOLL receptor-signaling pathway. 21609936 2011