Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
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0.360 | AlteredExpression | disease | BEFREE | The aim of the study was to analyse the expression of gene coding TNF alpha receptors R2 and R7 by estimation of mRNA expression of differentiated thyroid carcinomas in comparison to surrounding tissue free from neoplastic infiltration and search for differently spliced TNF alpha R2/R7 isophorms. | 12144133 | 2003 | ||||
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0.360 | AlteredExpression | disease | BEFREE | We analyzed DJ-1 expression in human thyroid carcinoma cell lines and the effect of DJ-1 on tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. | 18430896 | 2008 | ||||
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0.360 | GeneticVariation | disease | BEFREE | Tumor necrosis factorα (TNFα) G-308A (rs 1800629), interleukin-6 (IL-6) G-174C (rs 1800795) and IL-10 A-1082G (rs 1800896) single nucleotide polymorphisms in DNA from peripheral blood leukocytes of 190 patients with thyroid cancer and 216 healthy controls were investigated by real-time PCR combined with melting curve analysis. | 24464184 | 2014 | ||||
|
0.360 | Biomarker | disease | CTD_human | Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer. | 26037280 | 2015 | ||||
|
0.360 | Biomarker | disease | BEFREE | The membrane expression of CCR6 was assessed by flow cytometry and immunofluorescence, in primary cultures of normal human thyroid (NHT) cells and in thyroid cancer cell lines (TPC-1 and BCPAP), both in basal conditions and after stimulation with TNF-α. | 26577851 | 2016 | ||||
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0.360 | Biomarker | disease | BEFREE | Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) represents an effective agent for the treatment of many cancers, though the majority of thyroid cancers are found to be resistant. | 26721202 | 2016 | ||||
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0.360 | Biomarker | disease | BEFREE | Effect of Interferon-γ on the Basal and the TNFα-Stimulated Secretion of CXCL8 in Thyroid Cancer Cell Lines Bearing Either the RET/PTC Rearrangement Or the BRAF V600e Mutation. | 27555670 | 2016 |