Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6696
Gene Symbol: SPP1
SPP1 		0.560 Biomarker disease RGD Osteopontin expression in intratumoral astrocytes marks tumor progression in gliomas induced by prenatal exposure to N-ethyl-N-nitrosourea. 16651633 2006
Entrez Id: 208
Gene Symbol: AKT2
AKT2 		0.260 Biomarker disease RGD Reduction of Akt2 inhibits migration and invasion of glioma cells. 19330838 2009
Entrez Id: 2697
Gene Symbol: GJA1
GJA1 		0.260 Biomarker disease RGD Antitumor effects of monoclonal antibodies to connexin 43 extracellular fragment in induced low-differentiated glioma. 22808518 2012
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		0.260 Therapeutic disease RGD Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression. 19292920 2009
Entrez Id: 3371
Gene Symbol: TNC
TNC 		0.220 Biomarker disease RGD Human monoclonal antibodies to domain C of tenascin-C selectively target solid tumors in vivo. 16928692 2006
Entrez Id: 4233
Gene Symbol: MET
MET 		0.220 Biomarker disease RGD In vivo detection of c-Met expression in a rat C6 glioma model. 18194445 2008
Entrez Id: 63827
Gene Symbol: BCAN
BCAN 		0.210 Biomarker disease RGD A novel membrane-associated glycovariant of BEHAB/brevican is up-regulated during rat brain development and in a rat model of invasive glioma. 12799382 2003
Entrez Id: 2833
Gene Symbol: CXCR3
CXCR3 		0.210 Biomarker disease RGD Chemokine-directed migration of tumor-inhibitory neural progenitor cells towards an intracranially growing glioma. 16434036 2006
Entrez Id: 63827
Gene Symbol: BCAN
BCAN 		0.210 ModifyingMutation disease RGD Brain enriched hyaluronan binding (BEHAB)/brevican increases aggressiveness of CNS-1 gliomas in Lewis rats. 11585735 2001
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2 		0.210 Biomarker disease RGD Assessment of blood volume, vessel size, and the expression of angiogenic factors in two rat glioma models: a longitudinal in vivo and ex vivo study. 18615861 2008
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		0.210 Biomarker disease RGD Regression of intracerebral rat glioma isografts by therapeutic subcutaneous immunization with interferon-gamma, interleukin-7, or B7-1-transfected tumor cells. 10078962 1999
Entrez Id: 6480
Gene Symbol: ST6GAL1
ST6GAL1 		0.210 Therapeutic disease RGD Thus, manipulating ST6Gal I gene expression may have therapeutic potential for the treatment of malignant gliomas. 11559557 2001
Entrez Id: 10533
Gene Symbol: ATG7
ATG7 		0.200 Therapeutic disease RGD Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas. 25542083 2015
Entrez Id: 2147
Gene Symbol: F2
F2 		0.200 Therapeutic disease RGD The role of thrombin in gliomas. 15975137 2005
Entrez Id: 8089
Gene Symbol: YEATS4
YEATS4 		0.200 Biomarker disease RGD Expression, cellular distribution and protein binding of the glioma amplified sequence (GAS41), a highly conserved putative transcription factor. 11521196 2001
Entrez Id: 941
Gene Symbol: CD80
CD80 		0.200 Biomarker disease RGD Regression of intracerebral rat glioma isografts by therapeutic subcutaneous immunization with interferon-gamma, interleukin-7, or B7-1-transfected tumor cells. 10078962 1999
Entrez Id: 1508
Gene Symbol: CTSB
CTSB 		0.200 Biomarker disease RGD Cytosolic activation of cathepsins mediates parvovirus H-1-induced killing of cisplatin and TRAIL-resistant glioma cells. 17287256 2007
Entrez Id: 22933
Gene Symbol: SIRT2
SIRT2 		0.200 Therapeutic disease RGD Ultrasound-sensitive siRNA-loaded nanobubbles formed by hetero-assembly of polymeric micelles and liposomes and their therapeutic effect in gliomas. 23522375 2013
Entrez Id: 8877
Gene Symbol: SPHK1
SPHK1 		0.200 Biomarker disease RGD Modulation of P-glycoprotein function by sphingosine kinase-1 in brain endothelial cells. 17316399 2007
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		0.200 Therapeutic disease RGD Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases. 10830965 2000
Entrez Id: 6455
Gene Symbol: SH3GL1
SH3GL1 		0.200 ModifyingMutation disease RGD Autologous antibody to src-homology 3-domain GRB2-like 1 specifically increases in the sera of patients with low-grade gliomas. 23050879 2012
Entrez Id: 1435
Gene Symbol: CSF1
CSF1 		0.200 Biomarker disease RGD Antiangiogenic drugs synergize with a membrane macrophage colony-stimulating factor-based tumor vaccine to therapeutically treat rats with an established malignant intracranial glioma. 15728459 2005
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3 		0.200 ModifyingMutation disease RGD In malignant glioma, however, galectin-3 was expressed in both neoplastic astrocytic cells and microglia. 23179497 2013
Entrez Id: 374
Gene Symbol: AREG
AREG 		0.200 Biomarker disease RGD Increased expression of schwannoma-derived growth factor (SDGF) mRNA in rat tumor cells: involvement of SDGF in the growth promotion of rat gliomas. 8621257 1996
Entrez Id: 858
Gene Symbol: CAV2
CAV2 		0.200 Biomarker disease RGD Low-frequency ultrasound irradiation increases blood-tumor barrier permeability by transcellular pathway in a rat glioma model. 22528460 2012