Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		0.500 Biomarker disease MGD
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.330 Biomarker disease CTD_human
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.300 Biomarker disease CTD_human
Entrez Id: 25913
Gene Symbol: POT1
POT1 		0.300 Biomarker disease CTD_human
Entrez Id: 472
Gene Symbol: ATM
ATM 		0.110 CausalMutation disease CLINVAR
Entrez Id: 160140
Gene Symbol: C11orf65
C11orf65 		0.100 CausalMutation disease CLINVAR
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.050 PosttranslationalModification disease BEFREE "Smad"eningly erratic: target gene methylation determines whether TGFbeta promotes or suppresses malignant glioma. 17336898 2007
Entrez Id: 84868
Gene Symbol: HAVCR2
HAVCR2 		0.020 Biomarker disease BEFREE <b>Results</b>: TIM-3 was enriched in glioblastoma (the most malignant glioma) and IDH-wildtype glioma. 28919992 2017
Entrez Id: 706
Gene Symbol: TSPO
TSPO 		0.010 Biomarker disease BEFREE <sup>18</sup>F-GE-180, a novel TSPO ligand, has shown a high target-to-background contrast in HGG. 30244386 2019
Entrez Id: 367
Gene Symbol: AR
AR 		0.010 GeneticVariation disease BEFREE (4) LOH at the HUMARA locus is probably related to partial or complete deletion of an X-chromosome, which occurs in malignant gliomas during clonal evolution. 9343324 1997
Entrez Id: 1950
Gene Symbol: EGF
EGF 		0.100 GeneticVariation disease BEFREE Malignant gliomas are associated with alteration in EGF/EGFR signaling. 22481252 2012
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5 		0.320 GeneticVariation disease BEFREE Malignant glioma can be treated with radioiodine following transfection with human sodium iodide symporter (hNIS) gene. 25410753 2015
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		0.260 Biomarker disease BEFREE Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas. 10206300 1999
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.400 Biomarker disease BEFREE PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis. 10435616 1999
Entrez Id: 1634
Gene Symbol: DCN
DCN 		0.030 Biomarker disease BEFREE Decorin gene therapy for experimental malignant glioma is thought to involve antagonism of immunosuppression induced by glioma-derived transforming growth factor-beta (TGF-beta). 10496172 1999
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.100 AlteredExpression disease BEFREE Vascular endothelial growth factor expression is independent of hypoxia in human malignant glioma spheroids and tumours. 10682677 2000
Entrez Id: 3566
Gene Symbol: IL4R
IL4R 		0.040 Biomarker disease BEFREE Interleukin-13 receptor alpha chain: a novel tumor-associated transmembrane protein in primary explants of human malignant gliomas. 10728667 2000
Entrez Id: 573
Gene Symbol: BAG1
BAG1 		0.010 Biomarker disease BEFREE Bag-1 and Bcl-2 gene transfer in malignant glioma: modulation of cell cycle regulation and apoptosis. 10764042 2000
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1 		0.100 Biomarker disease BEFREE IFN-beta gene therapy induces systemic antitumor immunity against malignant glioma. 10982152 2000
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10 		0.400 Biomarker disease BEFREE TNF-related apoptosis-inducing ligand (TRAIL) is a potent inducer of apoptosis in adult malignant glioma and various other human solid tumor models but not in normal tissues. 11030149 2000
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS 		0.020 Biomarker disease BEFREE Glutathione S-transferase and drug sensitivity in malignant glioma. 11054494 2000
Entrez Id: 7276
Gene Symbol: TTR
TTR 		0.010 Biomarker disease BEFREE CTS1 gene transfer is a promising strategy of somatic gene therapy for malignant glioma. 11479223 2001
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 AlteredExpression disease BEFREE EGFR is overexpressed in a significant proportion of malignant gliomas in vivo. 11770895 2002
Entrez Id: 1755
Gene Symbol: DMBT1
DMBT1 		0.020 GeneticVariation disease BEFREE DMBT1 polymorphisms: relationship to malignant glioma tumorigenesis. 11912156 2002
Entrez Id: 3596
Gene Symbol: IL13
IL13 		0.050 AlteredExpression disease BEFREE Interleukin 13 (IL13) binds a receptor that is highly overexpressed in malignant gliomas, IL13Ralpha2. 15068667 2004