Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
0.330 AlteredExpression disease BEFREE A-raf gene amplification was more often detected and overexpression of all three RAF proteins on mRNA and protein level was regularly found in human malignant gliomas. 19082503 2009
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
0.330 Biomarker disease BEFREE These effects are distinct from our prior experience with VEGFR2 inhibitors, suggesting that targeting RAF itself or in combination with VEGFR2 induces profound tumor responses in gliomas and may serve as a novel therapeutic approach in patients with malignant gliomas. 16951188 2006
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
0.330 AlteredExpression disease BEFREE The RAF kinase inhibitor sorafenib suppresses ATF5 expression in glioma stem cells and inhibits malignant glioma growth in cell culture and mouse models. 20495567 2010
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
0.330 Biomarker disease CTD_human Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. 23583981 2013