Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS 		0.020 GeneticVariation disease BEFREE Glutathione S-transferase polymorphisms and survival in primary malignant glioma. 15102663 2004
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10 		0.400 Biomarker disease BEFREE TRAIL and malignant glioma. 15110189 2004
Entrez Id: 208
Gene Symbol: AKT2
AKT2 		0.260 Biomarker disease BEFREE PKB/Akt mediates radiosensitization by the signaling inhibitor LY294002 in human malignant gliomas. 15735908 2005
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		0.070 Biomarker disease BEFREE PKB/Akt mediates radiosensitization by the signaling inhibitor LY294002 in human malignant gliomas. 15735908 2005
Entrez Id: 2185
Gene Symbol: PTK2B
PTK2B 		0.010 Biomarker disease BEFREE PKB/Akt mediates radiosensitization by the signaling inhibitor LY294002 in human malignant gliomas. 15735908 2005
Entrez Id: 6382
Gene Symbol: SDC1
SDC1 		0.010 Biomarker disease BEFREE Syndecan-1 protein was localized in the cell surface of all malignant glioma cell lines by flow cytometry. 16132527 2006
Entrez Id: 23545
Gene Symbol: ATP6V0A2
ATP6V0A2 		0.010 AlteredExpression disease BEFREE RTF is thus a novel aberrantly expressed molecule which confers immune privilege to human malignant gliomas. 16585213 2006
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.100 Biomarker disease BEFREE VEGF and HIF-1alpha are elevated in malignant gliomas. 16612574 2006
Entrez Id: 2247
Gene Symbol: FGF2
FGF2 		0.340 Biomarker disease BEFREE Fibroblast growth factor-2-retargeted adenoviral vectors may be used to increase the transduction of GBM-derived endothelial cells, enabling a new and efficient antiangiogenesis strategy for the treatment of malignant gliomas. 16709032 2006
Entrez Id: 4179
Gene Symbol: CD46
CD46 		0.010 Biomarker disease BEFREE CD46 represents a target for adenoviral gene therapy of malignant glioma. 16716112 2006
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.400 Biomarker disease BEFREE PTEN gene transfer suppresses the invasive potential of human malignant gliomas by regulating cell invasion-related molecules. 16773187 2006
Entrez Id: 6657
Gene Symbol: SOX2
SOX2 		0.050 AlteredExpression disease BEFREE SOX2 was identified by screening an expression database for transcripts that are overexpressed in malignant glioma, but display minimal expression in normal tissues. 17375044 2007
Entrez Id: 110806265
Gene Symbol: MNS16A
MNS16A 		0.010 Biomarker disease BEFREE MNS16A has been investigated as a potential risk factor and/or prognostic marker for malignant glioma in a cohort of 352 patients (205 glioblastoma, 147 anaplastic gliomas) and 305 controls. 17410334 2007
Entrez Id: 1462
Gene Symbol: VCAN
VCAN 		0.010 Biomarker disease BEFREE Versican is a large chondroitin sulphate proteoglycan produced by several tumour cell types, including high-grade glioma. 17453002 2007
Entrez Id: 7490
Gene Symbol: WT1
WT1 		0.030 AlteredExpression disease BEFREE Wilms tumor 1 expression in malignant gliomas and correlation of +KTS isoforms with p53 status. 17886559 2007
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 Biomarker disease BEFREE EGFR tyrosine kinase inhibition radiosensitizes and induces apoptosis in malignant glioma and childhood ependymoma xenografts. 18386816 2008
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.050 AlteredExpression disease BEFREE TGF beta 1 and TGF beta 2 mRNA were expressed to a lesser degree among the hyperdiploid malignant gliomas. 1874566 1991
Entrez Id: 1356
Gene Symbol: CP
CP 		0.010 Biomarker disease BEFREE Ceruloplasmin is not only present in glioma cells and in human glioma specimens but also is enriched in highly malignant glioma stem-like cells. 18952589 2008
Entrez Id: 369
Gene Symbol: ARAF
ARAF 		0.010 AlteredExpression disease BEFREE A-raf gene amplification was more often detected and overexpression of all three RAF proteins on mRNA and protein level was regularly found in human malignant gliomas. 19082503 2009
Entrez Id: 2668
Gene Symbol: GDNF
GDNF 		0.330 Biomarker disease BEFREE Glial cell-line derived neurotrophic factor (GDNF) family of ligands confer chemoresistance in a ligand-specific fashion in malignant gliomas. 19138852 2009
Entrez Id: 2668
Gene Symbol: GDNF
GDNF 		0.330 Biomarker disease CTD_human Glial cell-line derived neurotrophic factor (GDNF) family of ligands confer chemoresistance in a ligand-specific fashion in malignant gliomas. 19138852 2009
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 GeneticVariation disease BEFREE EGFR variant III (EGFRvIII) is the most common EGFR mutation in malignant glioma. 19252415 2009
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 GeneticVariation disease BEFREE Epidermal growth factor receptor (EGFR) gene amplification, mutations, and/or aberrant activation are frequent abnormalities in malignant gliomas and other human cancers and have been associated with an aggressive clinical course and a poor therapeutic outcome. 19254954 2009
Entrez Id: 7010
Gene Symbol: TEK
TEK 		0.020 Biomarker disease BEFREE Tie2-mediated multidrug resistance in malignant gliomas is associated with upregulation of ABC transporters. 19421150 2009
Entrez Id: 2670
Gene Symbol: GFAP
GFAP 		0.100 AlteredExpression disease BEFREE Glial fibrillary acidic protein (GFAP), an intermediate filament protein normally found in astrocytes, and the radial glial marker brain fatty acid-binding protein (B-FABP; also known as FABP7) are co-expressed in malignant glioma cell lines and tumors. 19540848 2009