Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.400 GeneticVariation disease BEFREE To determine the prognostic value of isocitrate dehydrogenase 1 (IDH1) mutation, O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation, and 1p/19q co-deletion in Japanese patients with malignant gliomas. 24160898 2013
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.400 GeneticVariation disease BEFREE Of 158 tumors with sufficient tissue, 110 (70 %) showed nuclear cMYC immunopositivity--most frequent (95 %, χ(2) p = 0.0248) and intense (mean 1.33, ANOVA p = 0.0179) in anaplastic astrocytomas versus glioblastomas (63 %) or low grade gliomas (74 %). cMYC expression associated with younger age as well as p53 immunopositivity (OR = 3.6, p = 0.0332) and mutant IDH1 (R132H) (OR = 7.4, p = 0.06) among malignant gliomas in our cohort. 23934175 2013
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.400 GeneticVariation disease BEFREE Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas. 22869205 2012
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.400 Biomarker disease BEFREE Mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 are found frequently in malignant gliomas and are likely involved in early gliomagenesis. 22136423 2012
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.400 GeneticVariation disease BEFREE The interesting identification of an IDH1 mutation in a radiation-induced secondary malignant glioma raises the likelihood that these types of tumor may develop IDH1/2 mutations. 22821382 2012
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.400 GeneticVariation disease BEFREE IDH1 mutations are common in malignant gliomas in older children, suggesting that a subset of these lesions may be biologically similar to malignant gliomas arising in younger adults and may be associated with a more favorable prognosis. 20725730 2011
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.400 GeneticVariation disease BEFREE Polar spongioblastoma: A high-grade glioma that does not contain the IDH1 mutation or 1p/19q LOH. 20102524 2010
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.400 GeneticVariation disease BEFREE Similarly, in human malignant gliomas harbouring IDH1 mutations, we find markedly elevated levels of 2HG. 19935646 2009
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.400 Biomarker disease CTD_human NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. 19901110 2009
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.400 GeneticVariation disease BEFREE Mutations of NADP(+)-dependent isocitrate dehydrogenases encoded by IDH1 and IDH2 occur in a majority of several types of malignant gliomas. 19228619 2009