Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.330 SomaticCausalMutation disease ORPHANET
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.030 GeneticVariation disease BEFREE Histogenesis of diffuse small cleaved cell lymphoma. An immunohistochemical and molecular genetic (bcl-2 gene) study with comparison to follicular small cleaved cell lymphoma and mantle zone lymphoma. 1643614 1992
Entrez Id: 472
Gene Symbol: ATM
ATM
0.300 SomaticCausalMutation disease ORPHANET Mantle cell lymphoma is characterized by inactivation of the ATM gene. 10706620 2000
Entrez Id: 100820631
Gene Symbol: MLSM7
MLSM7
0.010 Biomarker disease BEFREE Statistical associations with FAB subtypes were found: aCLL and trisomy 12 (P < 0.00001); mantle zone lymphoma (MZL) and t(11;14) (P < 0.00001) and del(6)(q) (P < 0.0001); CLL/mixed cell type and del(6)(q) (P < 0.002); follicular lymphoma and t(14;18) (P < 0.00001); splenic lymphoma with villous lymphocytes and del(7)(q) (P < 0.0004); leukemic lymphoma (LL) with rearrangements in chromosome 9q (P < 0.0001) and trisomy of 3 (P < 0.001). 8609731 1995
Entrez Id: 3492
Gene Symbol: IGH
IGH
0.300 SomaticCausalMutation disease ORPHANET Templated nucleotide addition and immunoglobulin JH-gene utilization in t(11;14) junctions: implications for the mechanism of translocation and the origin of mantle cell lymphoma. 11245476 2001
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.030 GeneticVariation disease BEFREE These included 12 of 20 cases of nodular follicular center cell lymphoma (nine small cleaved cell, one mixed small and large cell, and two large cell types). bcl-2 translocation was detected in only three of 45 cases of diffuse B-cell lymphoma, and cases of AIDS-related malignant lymphoma, monocytoid B-cell lymphoma, and mantle zone lymphoma were all negative. 2263590 1990
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.030 GeneticVariation disease BEFREE These lesions include c-myc translocation and p53 inactivation in small noncleaved-cell lymphoma, and bcl-2 and bcl-1 translocation in follicular (FL) and mantle-zone lymphoma, respectively. 8172819 1994
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.330 GeneticVariation disease BEFREE These lesions include c-myc translocation and p53 inactivation in small noncleaved-cell lymphoma, and bcl-2 and bcl-1 translocation in follicular (FL) and mantle-zone lymphoma, respectively. 8172819 1994
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.330 GeneticVariation disease BEFREE We found oncogene rearrangements in five of the 14 cases: bcl-1 rearrangement on one mantle zone lymphoma, bcl-2 rearrangements in two follicular lymphomas, and c-myc rearrangements in two small noncleaved cell lymphomas. 8374527 1993
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.330 GeneticVariation disease BEFREE We report here one case of mantle zone lymphoma with a t(11;22)(q13;q11), a variant translocation at the BCL-1 locus, having the PRAD1 overexpression. 8280621 1993
Entrez Id: 3492
Gene Symbol: IGH
IGH
0.300 SomaticCausalMutation disease ORPHANET [Detection and analysis of bcl-1/IgH rearrangement in mantle cell lymphoma] 12601901 2002