Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23201
Gene Symbol: FAM168A
FAM168A
0.070 Biomarker disease BEFREE Tongue cancer resistance-associated protein 1 (TCRP1) is a novel gene located on human chromosome 11q13.4 which has been reported as a candidate related to chemotherapeutic resistance to cisplatin. 21603883 2011
Entrez Id: 23201
Gene Symbol: FAM168A
FAM168A
0.070 Biomarker disease BEFREE Tongue cancer resistance-associated protein 1 (TCRP1) gene was recently cloned and reported to specially mediate DDP resistance in human oral squamous cell carcinoma (OSCC) cells. 25260657 2015
Entrez Id: 23201
Gene Symbol: FAM168A
FAM168A
0.070 Biomarker disease BEFREE Tongue cancer resistance-related protein 1 (TCRP1) gene was first cloned from the multidrug resistance tongue cancer cell (Tca8113/pingyangmycin) in our lab. 28436990 2017
Entrez Id: 23201
Gene Symbol: FAM168A
FAM168A
0.070 Biomarker disease BEFREE Tongue cancer resistance-associated protein 1 (TCRP1) is a newly identified gene, which was cloned from a multi-drug resistant cell line of tongue cancer. 28454268 2017
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.020 AlteredExpression disease BEFREE Bcl-2 expression played a minor role in oral tongue carcinoma. 12359206 2002
Entrez Id: 573
Gene Symbol: BAG1
BAG1
0.010 AlteredExpression disease BEFREE BAG-1 expression was evaluated by immunohistochemistry in paraffin-embedded tissues of leukoplakia (n=25) and carcinoma of the tongue (n=61). 17549665 2007
Entrez Id: 4317
Gene Symbol: MMP8
MMP8
0.020 Biomarker disease BEFREE Collagenase-2 (matrix metalloproteinase-8) plays a protective role in tongue cancer. 18253113 2008
Entrez Id: 64946
Gene Symbol: CENPH
CENPH
0.010 AlteredExpression disease BEFREE CENP-H expression was higher in tongue cancer cell lines and cancer tissues (T) than that in normal cell and adjacent noncancerous tongue tissues (N), respectively. 19500341 2009
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
0.050 AlteredExpression disease BEFREE Notch1 and jagged1 were significantly more highly expressed in lymph node metastasis-positive tongue carcinoma (χ² = 6.108, P = 0.013; χ² = 7.354, P = 0.025). 20819128 2011
Entrez Id: 10904
Gene Symbol: BLCAP
BLCAP
0.010 AlteredExpression disease BEFREE BLCAP is ubiquitously expressed in different tissues, and several studies have found differential expression of BLCAP in various cancer types, such as cervical and renal cancer, as well as human tongue carcinoma and osteosarcoma. 23049907 2012
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.100 GeneticVariation disease BEFREE TP53 Pro72 allele is enriched in oral tongue cancer and frequently mutated in esophageal cancer in India. 25436609 2014
Entrez Id: 857
Gene Symbol: CAV1
CAV1
0.010 Biomarker disease BEFREE Caveolin-1 accumulation in the tongue cancer tumor microenvironment is significantly associated with poor prognosis: an in-vivo and in-vitro study. 25633184 2015
Entrez Id: 768
Gene Symbol: CA9
CA9
0.020 Biomarker disease BEFREE Carbonic anhydrase 9 (CA9) has been shown to be upregulated in the drug-resistant tongue cancer cell line Tca8113/PYM and to be associated with drug resistance. 25890268 2015
Entrez Id: 356
Gene Symbol: FASLG
FASLG
0.010 GeneticVariation disease BEFREE FASL variants (GA and AA) increased tongue cancer risk in females who were tobacco users compared to non-tobacco users. 25944167 2015
Entrez Id: 4613
Gene Symbol: MYCN
MYCN
0.010 AlteredExpression disease BEFREE MYCN-mediated miR-21 overexpression enhances chemo-resistance via targeting CADM1 in tongue cancer. 27055844 2016
Entrez Id: 23705
Gene Symbol: CADM1
CADM1
0.010 Biomarker disease BEFREE CADM1 sensitizes tongue cancer cells to chemotherapy. 27055844 2016
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
0.040 Biomarker disease BEFREE microRNA-21 and microRNA-375 from oral cytology as biomarkers for oral tongue cancer detection. 27208839 2016
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.050 Biomarker disease BEFREE MALAT1 induces tongue cancer cells' EMT and inhibits apoptosis through Wnt/β-catenin signaling pathway. 27353727 2017
Entrez Id: 10657
Gene Symbol: KHDRBS1
KHDRBS1
0.010 Biomarker disease BEFREE Sam68 reduces cisplatin-induced apoptosis in tongue carcinoma. 27473117 2016
Entrez Id: 8076
Gene Symbol: MFAP5
MFAP5
0.010 Biomarker disease BEFREE MFAP5 and TNNC1: Potential markers for predicting occult cervical lymphatic metastasis and prognosis in early stage tongue cancer. 27713166 2017
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
0.010 Biomarker disease BEFREE FDG PET/CT in Carcinoma of the Tongue With Bilateral Adrenal Metastases. 27997430 2017
Entrez Id: 406932
Gene Symbol: MIR140
MIR140
0.010 Biomarker disease BEFREE MiR-140-5p is a small, non-coding single-stranded RNA molecule, which was previously studied in the settings of human tongue cancer, hepatocellular carcinoma, and colorectal cancer. 28443475 2017
Entrez Id: 8828
Gene Symbol: NRP2
NRP2
0.010 AlteredExpression disease BEFREE Nrp2 expression in early tongue cancer was investigated to predict lymph node metastasis and the long-term prognosis. 28602571 2017
Entrez Id: 406959
Gene Symbol: MIR183
MIR183
0.010 Biomarker disease BEFREE miR-183 and miR-21 expression as biomarkers of progression and survival in tongue carcinoma patients. 28616749 2018
Entrez Id: 652995
Gene Symbol: UCA1
UCA1
0.010 Biomarker disease BEFREE UCA1 knockdown significantly suppressed TGFβ1-induced tongue cancer cell invasion and EMT by decreasing vimentin and increasing E-cadherin. 30635938 2019