| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | AlteredExpression | disease | BEFREE | Epidermal growth factor receptor (EGFR) and activin A are both overexpressed in oral cavity squamous cell carcinoma (OSCC). | 30914776 | 2019 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | To exclude the effect of EGFR gene copy number on protein overexpression, only those OSCC tumors with disomy of the EGFR gene were included in further analysis. | 28694429 | 2017 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | EGFR copy number alterations in primary tumors, metastatic lymph nodes, and recurrent and multiple primary tumors in oral cavity squamous cell carcinoma. | 28854970 | 2017 | ||||
|
0.080 | Biomarker | disease | BEFREE | Hence the aims were (1) to estimate disease-free survival, overall survival, and cause-specific survival in patients who developed oral cavity squamous cell carcinoma between 18 and 40 years of age and (2) to assess the clinicopathologic factors including detection of human papillomavirus and epidermal growth factor receptor (EGFR) overexpression in primary lesions affecting recurrence. | 22387125 | 2013 | ||||
|
0.080 | Biomarker | disease | BEFREE | Standard methodological and interpretation criteria need to be established that allows EGFR copy number combined with EGFR protein expression to be determined in a manner that allows individualized EGFR targeted therapy in OSCC patients. | 21831696 | 2012 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | We identified a high frequency of Q787Q mutation and a less prevalent active EGFR mutation in OSCC patients in Taiwan where betel nut is commonly chewed. | 21284055 | 2011 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | EGFR protein overexpression and mutation in areca quid-associated oral cavity squamous cell carcinoma in Taiwan. | 19360742 | 2009 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | The degree of gene amplification for epidermal growth factor receptor (EGFR) and its expression levels were examined in 4 cases of tumor lesions and their cell lines of human squamous cell carcinoma (SCC) of the oral cavity. | 1624295 | 1992 |