| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | GeneticVariation | disease | BEFREE | In the current special article we explored the role of the p53 gene deregulation - especially focused on its mutation status - in OCSCCs. | 30610778 | 2019 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | In conclusion, HPV was shown to be an uncommon association with OCSCC and changes in TP53 transcriptional regulation, mTOR signaling and mitochondrial function were associated with a history of tobacco use. | 30308005 | 2018 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Our results demonstrate the usefulness of TP53 DBD missense mutations combined with clinicopathological factors for improving the prognostic stratification of OSCC patients. | 27283772 | 2016 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Increased expression rate of p53 and/or decreased maspin expression rate were significantly higher in oral cavity SCC than normal tissues. | 24801268 | 2015 | ||||
|
0.090 | Biomarker | disease | BEFREE | Taken together, these results indicate that NTP induced apoptotic cell death in p53 wild-type OSCCs through a novel mechanism involving DNA damage and triggering of sub-G(1) arrest via the ATM/p53 pathway. | 24486404 | 2014 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | CONCLUSION The results indicate that the loss of function (transactivation activities) of p53 mutant proteins may predict a significant low pCR rate and suboptimal response to cisplatin-based neoadjuvant chemotherapy in patients with oral cavity SCC. | 20048189 | 2010 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | We sought to determine the frequency and type of p53 mutations in squamous cell carcinomas (SCC) of the oral cavity in a Brazilian population. | 14719105 | 2004 | ||||
|
0.090 | Biomarker | disease | BEFREE | An analysis of the prognostic significance of p53 status for squamous cell carcinoma of the oral cavity treated by radiotherapy. | 9930364 | 1998 | ||||
|
0.090 | PosttranslationalModification | disease | BEFREE | These results suggest that inactivation of p53 is involved in the development or progression of SCC of the oral cavity. | 8443743 | 1993 |