Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.100 Biomarker disease BEFREE In summary, we report a novel mechanism where biglycan through a LRP6/β-catenin/IGF-IR signaling axis enhances osteosarcoma cell growth. 30406034 2018
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.100 Biomarker disease BEFREE This review article focused on the role of IGF-1/IGF-1R in OS progression and therapeutic aspects of OS targeting IGF-1. 30217668 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.100 Biomarker disease BEFREE Furthermore, we also observed that suppression of IGF-1R could reduce the invasiveness of osteosarcoma cells and enhance their radiosensitivity. 19229591 2009
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.100 Biomarker disease BEFREE Evidence for modulation of osteocalcin containing gamma-carboxyglutamic acid residues synthesis by insulin-like growth factor-I and vitamin K2 in human osteosarcoma cell line MG-63. 9578515 1998
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.100 AlteredExpression disease BEFREE Insulin-like growth factor-I induces cyclin-D1 expression in MG63 human osteosarcoma cells in vitro. 8052269 1994