Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
0.100 AlteredExpression disease BEFREE Therefore, it can be concluded that through the inhibition of CD44 expression levels, miR-34a plays a significant role in the migration and invasion of osteosarcoma cells. 23314380 2013
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
0.100 Biomarker disease BEFREE These results indicated that NEAT1 participated in the development of osteosarcoma as a ceRNA to competitively bind to miR-34a-5p and thus mediate HOXA13 expression. 31044561 2019
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
0.100 Biomarker disease BEFREE This study suggested that miR-34a-5p, DLL1 and the ATF2/ATF3/ATF4 signaling pathway-associated genes are the potential diagnostic and/or therapeutic targets for an effective chemotherapy of OS. 28281638 2017
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
0.100 AlteredExpression disease BEFREE Treatment of U2OS cells with cisplatin induced cell apoptosis by upregulation of c-Myc -dependent Bim expression; Osteosarcoma U2OS cells transfected with miR-34a mimics (miR-34a/U2OS) induced cell apoptosis and inhibited cell survival, and increased the sensitivity of U2OS cells to cisplatin. 29060932 2017
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
0.100 Biomarker disease BEFREE Validating the coordinating role of miR-34a in microtubule destabilization, when miR-34a was combined with either microtubule inhibitors or chemotherapy, STMN1 phosphorylation was suppressed and there was greater cytotoxicity in osteosarcoma cells. 28275089 2017
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
0.100 AlteredExpression disease BEFREE We also found that reexpression of miR-34a and miR-200b by transfection led to reduced expression of Notch-1, resulting in the inhibition of osteosarcoma cell proliferation, invasion and angiogenesis. 23430952 2013