Gene: HMGB1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		0.100 AlteredExpression disease BEFREE In addition, HMGB1 was highly expressed in osteosarcoma tissues (P<0.01), with a significantly negative correlation with miR-505 (r=-0.6679, P<0.001). 29251324 2018
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		0.100 Biomarker disease BEFREE Therefore, HMGB1 may be a potential target in molecular therapy for patients with osteosarcoma. 29387198 2018
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		0.100 AlteredExpression disease BEFREE Furthermore, a significant negative association was found between miR-935 and HMGB1 mRNA expression in OS tissues. 29471892 2018
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		0.100 Biomarker disease BEFREE miRNA-1284, a regulator of HMGB1, inhibits cell proliferation and migration in osteosarcoma. 29899164 2018
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		0.100 GeneticVariation disease BEFREE Spinal PKC activation - Induced neuronal HMGB1 translocation contributes to hyperalgesia in a bone cancer pain model in rats. 29428215 2018
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		0.100 Biomarker disease BEFREE Together, our results support a MALAT1/miR-142-3p/miR-129-5p/HMGB1 axis in OS cell proliferation and tumor progression. 28346809 2017
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		0.100 Biomarker disease BEFREE HMGB1-induced autophagy promotes tumor resistance to chemotherapy, as shown in different models of malignancy, for example, osteosarcoma, leukemia, and gastric cancer. 26925422 2016
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		0.100 Biomarker disease BEFREE HMGB1 Osteo-Modulatory Action on Osteosarcoma SaOS-2 Cell Line: An Integrated Study From Biochemical and -Omics Approaches. 27012556 2016
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		0.100 Biomarker disease BEFREE Recent studies have demonstrated that the high mobility group box 1 (HMGB1)-mediated autophagy promotes chemoresistance in osteosarcoma, lung adenocarcinoma and ovarian cancer, but the exact molecular mechanism underlying HMGB1-mediated autophagy in NB has not been clearly defined. 26397184 2015
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		0.100 Biomarker disease BEFREE Our study suggests a complexity in the regulation of autophagy by miR-22 and HMGB1 during chemotherapy resistance in osteosarcoma. 24609901 2014
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		0.100 Biomarker disease BEFREE In summary, this study implied the negative regulation of miR-22 on the HMGB1-mediated autophagy in osteosarcoma cells. 24752578 2014
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		0.100 AlteredExpression disease BEFREE In order to explore the role of HMGB1 in osteosarcoma, the expression of HMGB1 in the human osteosarcoma MG-63 cell line was downregulated by the technique of RNA interference. 25168370 2014