Overexpression of cytosolic phospholipase A2 (cPLA<sub>2</sub>) has been shown to promote progression in several types of cancers, but its functions in OS have not been investigated.
Moreover, with the protection of acetone against tissue antigenicity, we successfully characterized the expression of three metabolites-related enzymes, fatty acid synthase (FASN), glutaminase (GLS), and cytosolic phospholipase A2 (cPLA2) in osteosarcoma.